Literature DB >> 10757726

7-Epicylindrospermopsin, a toxic minor metabolite of the cyanobacterium Aphanizomenon ovalisporum from lake Kinneret, Israel.

R Banker1, B Teltsch, A Sukenik, S Carmeli.   

Abstract

A toxic minor metabolite, 7-epicylindrospermopsin (1), was isolated from a culture of the cyanobacterium Aphanizomenon ovalisporum isolated from Lake Kinneret in Israel. Homonuclear and inverse-heteronuclear 2D NMR techniques, as well as HRMS and comparison of the NMR data with model compounds, enabled the structure determination of the new compound. Four polymethoxy-1-alkenes, 3-6, were isolated from the lipophilic extract of the cyanobacterium as well.

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Year:  2000        PMID： 10757726     DOI： 10.1021/np990498m

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  25 in total

1.  The interactive effects of microcystin-LR and cylindrospermopsin on the growth rate of the freshwater algae Chlorella vulgaris.

Authors:  Carlos Pinheiro; Joana Azevedo; Alexandre Campos; Vítor Vasconcelos; Susana Loureiro
Journal:  Ecotoxicology       Date:  2016-02-24       Impact factor: 2.823

Review 2.  Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism.

Authors:  Robert M Williams
Journal:  J Org Chem       Date:  2011-04-12       Impact factor: 4.354

3.  Biosynthesis of cylindrospermopsin and 7-epicylindrospermopsin in Oscillatoria sp. strain PCC 6506: identification of the cyr gene cluster and toxin analysis.

Authors:  Rabia Mazmouz; Florence Chapuis-Hugon; Stéphane Mann; Valérie Pichon; Annick Méjean; Olivier Ploux
Journal:  Appl Environ Microbiol       Date:  2010-06-04       Impact factor: 4.792

4.  Biosynthetic origin of the 3-amino-2,5,7,8-tetrahydroxy-10-methylundecanoic acid moiety and absolute configuration of pahayokolides A and B.

Authors:  Li Liu; Daniel W Bearden; Kathleen S Rein
Journal:  J Nat Prod       Date:  2011-06-08       Impact factor: 4.050

5.  Sporadic distribution and distinctive variations of cylindrospermopsin genes in cyanobacterial strains and environmental samples from Chinese freshwater bodies.

Authors:  Yongguang Jiang; Peng Xiao; Gongliang Yu; Jihai Shao; Deming Liu; Sandra M F O Azevedo; Renhui Li
Journal:  Appl Environ Microbiol       Date:  2014-06-13       Impact factor: 4.792

6.  New Tricks in Amino Acid Synthesis: Applications to Complex Natural Products.

Authors:  Robert M Williams; Cameron M Burnett
Journal:  ACS Symp Ser Am Chem Soc       Date:  2009-06-14

Review 7.  Cylindrospermopsin: a decade of progress on bioaccumulation research.

Authors:  Susan Kinnear
Journal:  Mar Drugs       Date:  2010-03-09       Impact factor: 5.118

8.  High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance of Intact Zebrafish Embryos Detects Metabolic Changes Following Exposure to Teratogenic Polymethoxyalkenes from Algae.

Authors:  John P Berry; Upasana Roy; Asha Jaja-Chimedza; Kristel Sanchez; Joerg Matysik; A Alia
Journal:  Zebrafish       Date:  2016-06-27       Impact factor: 1.985

9.  Aphanizomenon gracile (Nostocales), a cylindrospermopsin-producing cyanobacterium in Polish lakes.

Authors:  Mikołaj Kokociński; Joanna Mankiewicz-Boczek; Tomasz Jurczak; Lisa Spoof; Jussi Meriluoto; Edyta Rejmonczyk; Henna Hautala; Markus Vehniäinen; Jakub Pawełczyk; Janne Soininen
Journal:  Environ Sci Pollut Res Int       Date:  2013-02-02       Impact factor: 4.223

10.  Identification of teratogenic polymethoxy-1-alkenes from Cylindrospermopsis raciborskii, and taxonomically diverse freshwater cyanobacteria and green algae.

Authors:  Asha Jaja-Chimedza; Christopher Saez; Kristel Sanchez; Miroslav Gantar; John P Berry
Journal:  Harmful Algae       Date:  2015-11-01       Impact factor: 4.273
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