| Literature DB >> 10757719 |
B Chen1, K Kawazoe, Y Takaishi, G Honda, M Itoh, Y Takeda, O K Kodzhimatov, O Ashurmetov.
Abstract
Four new prenylated benzoic acid derivatives, kuhistanols A-D (1-4), along with one known compound, 3-farnesyl-p-hydroxybenzoic acid (5), have been isolated from the roots of the Uzbekistan medicinal plant, Ferula kuhistanica. Their structures were established on the basis of chemical and spectral evidence. Compound 4 showed a significant inhibitory effect on cytokine production in lipopolysaccharide-stimulated human peripheral mononuclear cells.Entities:
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Year: 2000 PMID： 10757719 DOI： 10.1021/np990338a
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050