Literature DB >> 10756154

Sin nombre virus (SNV) Ig isotype antibody response during acute and convalescent phases of hantavirus pulmonary syndrome.

P Bostik1, J Winter, T G Ksiazek, P E Rollin, F Villinger, S R Zaki, C J Peters, A A Ansari.   

Abstract

Serum samples from 22 hantavirus pulmonary syndrome (HPS) patients were tested for Sin Nombre virus (SNV)-reactive antibodies. In the acute phase of HPS, 100% and 67% of the samples tested positive for SNV-specific immunoglobulin (Ig) M and IgA, respectively. Among the virus-specific IgG antibodies, the most prevalent were IgG3 (in 97% of samples), followed by IgG1 (70%), IgG2 (30%), and IgG4 (3%).

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Year:  2000        PMID： 10756154      PMCID： PMC2640842          DOI： 10.3201/eid0602.000213

Source DB:  PubMed          Journal:  Emerg Infect Dis        ISSN： 1080-6040            Impact factor:   6.883


  15 in total

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