Literature DB >> 10755336

Gracilis transposition in complicated perianal fistula and unhealed perineal wounds in Crohn's disease.

J Rius1, A Nessim, J J Nogueras, S D Wexner.   

Abstract

OBJECTIVE: To assess the efficacy of transposition of gracilis muscle in the treatment of chronic recurrent fistulas and unhealed perineal wounds after proctectomy in patients with Crohn's disease.
DESIGN: Retrospective study.
SETTING: Academic clinic, United States.
SUBJECTS: 7 patients with Crohn's disease: 3 had unhealed perineal wounds and persistent sinuses; 2 had had several attempts to repair rectovaginal fistulas; 1 had a rectourethral fistula; and 1 a pouch vaginal fistula. INTERVENTION: Transposition of the gracilis muscle. MAIN OUTCOME MEASURE: Healing.
RESULTS: Mean follow up was 18 months (range 3-30). All patients operated on for unhealed perineal wounds had healed completely within 3-6 months. The patients with a rectovaginal fistula and a rectourethral fistula had both healed by 1 month postoperatively. Two fistulas recurred, and the small pouch-vaginal fistula remained but was asymptomatic.
CONCLUSIONS: Transposition of the gracilis is a viable option for the treatment of persistent sinus and unhealed perineal wound after proctectomy for Crohn's disease. It could also be an option before proctectomy for patients with other types of Crohn's-related or complicated fistulas for whom other treatments have failed. A larger series will be required before a definite conclusion can be drawn.

Entities:  

Mesh:

Year:  2000        PMID: 10755336     DOI: 10.1080/110241500750009311

Source DB:  PubMed          Journal:  Eur J Surg        ISSN: 1102-4151


  23 in total

1.  Autologous stem cell transplantation for treatment of rectovaginal fistula in perianal Crohn's disease: a new cell-based therapy.

Authors:  Damian García-Olmo; Mariano García-Arranz; Lourdes Gómez García; Eduardo Serna Cuellar; Ignacio Fernández Blanco; Luis Asensio Prianes; José Antonio Rodríguez Montes; Francisca Lima Pinto; Dolores Herreros Marcos; Luis García-Sancho
Journal:  Int J Colorectal Dis       Date:  2003-05-20       Impact factor: 2.571

2.  [Persistent perineal sinus closure after rectal extirpation-an alternative using bulbocavernosus fat flaps].

Authors:  M Kaminski; M Sippel; A Hirner
Journal:  Chirurg       Date:  2004-06       Impact factor: 0.955

3.  Graciloplasty for rectourethral, rectovaginal and rectovesical fistulas: technique overview, pitfalls and complications.

Authors:  D Ruiz; B Bashankaev; J Speranza; S D Wexner
Journal:  Tech Coloproctol       Date:  2008-08-05       Impact factor: 3.781

4.  Perianal Crohn's disease.

Authors:  Bashar Safar; Dana Sands
Journal:  Clin Colon Rectal Surg       Date:  2007-11

5.  Management of nonhealing perineal wounds.

Authors:  Jill C Genua; David A Vivas
Journal:  Clin Colon Rectal Surg       Date:  2007-11

Review 6.  Surgical treatment of anorectal crohn disease.

Authors:  Robert T Lewis; Joshua I S Bleier
Journal:  Clin Colon Rectal Surg       Date:  2013-06

7.  Proctocolectomy and brooke ileostomy for chronic ulcerative colitis.

Authors:  Eric J Dozois
Journal:  Clin Colon Rectal Surg       Date:  2004-02

8.  Reoperative inflammatory bowel disease surgery.

Authors:  Rowena L Ramirez; Phillip Fleshner
Journal:  Clin Colon Rectal Surg       Date:  2006-11

9.  Adipose-derived stem cells in Crohn's rectovaginal fistula.

Authors:  D García-Olmo; D Herreros; P De-La-Quintana; H Guadalajara; J Trébol; T Georgiev-Hristov; M García-Arranz
Journal:  Case Rep Med       Date:  2010-03-07

Review 10.  Persistent perineal sinus: incidence, pathogenesis, risk factors, and management.

Authors:  Varut Lohsiriwat
Journal:  Surg Today       Date:  2009-03-12       Impact factor: 2.549

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