Literature DB >> 10754683

Understanding enediyne-protein interactions: diyl atom transfer results in generation of aminoacyl radicals.

G B Jones1, G W Plourde, J M Wright.   

Abstract

[formula: see text] The origin of the protein modulating capacity of enediynes has been probed. A series of synthetic enediyne-derived diyls participated in atom transfer chemistry with a labeled amino acid. Subsequent experiments suggest that diyl radicals may modulate protein architecture via formation of captodatively stabilized radicals.

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Year:  2000        PMID： 10754683     DOI： 10.1021/ol0055566

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab.

Authors:  Subhash C Sinha; Lian-Sheng Li; Gregory P Miller; Shantanu Dutta; Christoph Rader; Richard A Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-23       Impact factor: 11.205

2.  Reactivity and selectivity of charged phenyl radicals toward amino acids in a Fourier transform ion cyclotron resonance mass spectrometer.

Authors:  George O Pates; Leonard Guler; John J Nash; Hilkka I Kenttämaa
Journal:  J Am Chem Soc       Date:  2011-05-25       Impact factor: 15.419

3.  Reactions of an aromatic σ,σ-biradical with amino acids and dipeptides in the gas phase.

Authors:  Mingkun Fu; Sen Li; Enada Archibold; Michael J Yurkovich; John J Nash; Hilkka I Kenttämaa
Journal:  J Am Soc Mass Spectrom       Date:  2010-06-25       Impact factor: 3.109

4.  A novel enediynyl peptide inhibitor of furin that blocks processing of proPDGF-A, B and proVEGF-C.

Authors:  Ajoy Basak; Abdel-Majid Khatib; Dayani Mohottalage; Sarmistha Basak; Maria Kolajova; Subhendu Sekhar Bag; Amit Basak
Journal:  PLoS One       Date:  2009-11-26       Impact factor: 3.240
  4 in total

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