Literature DB >> 10754535

PPAR delta functions as a prostacyclin receptor in blastocyst implantation.

H Lim1, S K Dey.   

Abstract

Peroxisome proliferator-activated receptors (PPARs), members of the nuclear hormone superfamily, are the target of extensive investigation because of their role in various pathophysiological processes. Recently, a novel biological function of PPAR delta, a less studied member of the family, was observed in the mouse. Evidence suggests that cyclooxygenase 2-derived prostacyclin mediates blastocyst implantation via this receptor. In this review, this new function of PPAR delta in implantation is highlighted, and future directions to investigate its mechanism of action are discussed.

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Year:  2000        PMID： 10754535     DOI： 10.1016/s1043-2760(00)00243-5

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  18 in total

Review 1.  Vascular effects of prostacyclin: does activation of PPARδ play a role?

Authors:  Zvonimir S Katusic; Anantha V Santhanam; Tongrong He
Journal:  Trends Pharmacol Sci       Date:  2012-06-23       Impact factor: 14.819

Review 2.  Peroxisome proliferator-activated receptor-delta, a regulator of oxidative capacity, fuel switching and cholesterol transport.

Authors:  C Fürnsinn; T M Willson; B Brunmair
Journal:  Diabetologia       Date:  2006-11-22       Impact factor: 10.122

3.  Differential peroxisome proliferator activated receptors activity in a rodent model of amyotrophic lateral sclerosis.

Authors:  Yan Qi; Xiang Yin; Shuyu Wang; Jing Wang; Hongquan Jiang; Xudong Wang; Ming Ren; Honglin Feng
Journal:  Int J Clin Exp Med       Date:  2015-03-15

Review 4.  PPAR-γ -- a possible drug target for complicated pregnancies.

Authors:  Fergus P McCarthy; Aoife C Delany; Louise C Kenny; Sarah K Walsh
Journal:  Br J Pharmacol       Date:  2013-03       Impact factor: 8.739

5.  Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta.

Authors:  Karim Nadra; Silvia I Anghel; Elisabeth Joye; Nguan Soon Tan; Sharmila Basu-Modak; Didier Trono; Walter Wahli; Béatrice Desvergne
Journal:  Mol Cell Biol       Date:  2006-04       Impact factor: 4.272

6.  Lysophosphatidic acid attenuates the cytotoxic effects and degree of peroxisome proliferator-activated receptor gamma activation induced by 15-deoxyDelta12,14-prostaglandin J2 in neuroblastoma cells.

Authors:  Helen A Rodway; Alan N Hunt; Janice A Kohler; Anthony D Postle; Karen A Lillycrop
Journal:  Biochem J       Date:  2004-08-15       Impact factor: 3.857

7.  The PPARδ ligand GW501516 reduces growth but not apoptosis in mouse inner medullary collecting duct cells.

Authors:  Jordan Clark; Rania Nasrallah; Richard L Hébert
Journal:  PPAR Res       Date:  2009-03-04       Impact factor: 4.964

8.  Current understanding of the role of PPARγ in gastrointestinal cancers.

Authors:  Bing Zou; Liang Qiao; Benjamin C Y Wong
Journal:  PPAR Res       Date:  2009-10-26       Impact factor: 4.964

Review 9.  Peroxisome proliferator-activated receptor targets for the treatment of metabolic diseases.

Authors:  Francisco A Monsalve; Radha D Pyarasani; Fernando Delgado-Lopez; Rodrigo Moore-Carrasco
Journal:  Mediators Inflamm       Date:  2013-05-27       Impact factor: 4.711

10.  PPAR Action in Human Placental Development and Pregnancy and Its Complications.

Authors:  Fritz Wieser; Leslie Waite; Christophe Depoix; Robert N Taylor
Journal:  PPAR Res       Date:  2008       Impact factor: 4.964
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