Literature DB >> 10753593

Diabetic retinopathy is associated with decreased serum levels of free IGF-I and changes of IGF-binding proteins.

B Feldmann1, P M Jehle, S Mohan, G E Lang, G K Lang, J Brueckel, B O Boehm.   

Abstract

In patients with diabetic retinopathy, elevated serum levels of total circulating insulin-like growth factor-I (IGF-I) have been implicated as an important mediator of the disease. There is no study, however, measuring free IGF-I levels in patients with diabetic retinopathy which mediate the biological effects of IGF-I and are modulated by a complex system of six specific IGF binding proteins (IGFBPs) and several IGFBP proteases. Copyright 2000 Harcourt Publishers Ltd.

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Year:  2000        PMID： 10753593     DOI： 10.1054/ghir.2000.0140

Source DB:  PubMed          Journal:  Growth Horm IGF Res        ISSN： 1096-6374            Impact factor:   2.372


  5 in total

1.  Longitudinal relation between limited joint mobility, height, insulin-like growth factor 1 levels, and risk of developing microalbuminuria: the Oxford Regional Prospective Study.

Authors:  R Amin; T K Bahu; B Widmer; R N Dalton; D B Dunger
Journal:  Arch Dis Child       Date:  2005-10       Impact factor: 3.791

2.  The IGF-Axis and Diabetic Retinopathy Before and After Gastric Bypass Surgery.

Authors:  Troels Brynskov; Caroline Schmidt Laugesen; Andrea Karen Floyd; Jan Frystyk; Torben Lykke Sørensen
Journal:  Obes Surg       Date:  2017-02       Impact factor: 4.129

3.  Serum insulin-like growth factor binding protein 6 (IGFBP6) is increased in patients with type 1 diabetes and its complications.

Authors:  Shangsu Lu; Sharad Purohit; Ashok Sharma; Wenbo Zhi; Mingfang He; Yiqian Wang; Chao-Jun Li; Jin-Xiong She
Journal:  Int J Clin Exp Med       Date:  2012-06-10

Review 4.  An ocular view of the IGF-IGFBP system.

Authors:  Dung V Nguyen; Sergio Li Calzi; Lynn C Shaw; Jennifer L Kielczewski; Hannah E Korah; Maria B Grant
Journal:  Growth Horm IGF Res       Date:  2013-04-08       Impact factor: 2.372

Review 5.  Insulin-Like Growth Factor Binding Proteins in Autoimmune Diseases.

Authors:  Huihua Ding; Tianfu Wu
Journal:  Front Endocrinol (Lausanne)       Date:  2018-08-30       Impact factor: 5.555
  5 in total

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