Literature DB >> 10753250

Correlations of cardiovascular disease risk factors between African American siblings.

R J Iannotti1, A E Zuckerman, N Rifai.   

Abstract

OBJECTIVES: This study examines intrasibling correlations at 2 points during childhood for African American siblings with the same father, different fathers, a father present in the home, and no father present in the home. STUDY
DESIGN: Cardiovascular disease (CVD) risk factors were assessed in 267 pairs of African American siblings (visit 1) and in 79 of these siblings approximately 28 months later (visit 2).
RESULTS: As a group, correlations of CVD risk factors between African American siblings with the same father were greater than those for African American siblings with different fathers in visit 1 (P <.05). However, having a father present in the home was associated with significantly lower intrasibling correlations for girth and total cholesterol in visit 2 (P <.005). Intrasibling correlations for the 4 family subgroups suggest that CVD risk factors were most similar in siblings who shared the same father but who had no father present in the home.
CONCLUSIONS: Intrasibling correlations for African American children were influenced by whether they shared the same father and whether a father was present in their home, reflecting both genetic and environmental influences. Family composition should be considered when family CVD risk factors are used to predict CVD risk in children.

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Year:  2000        PMID: 10753250     DOI: 10.1016/s0022-3476(00)90015-5

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  1 in total

1.  The importance of early life family factors in the association between cardiovascular risk factors and early cardiovascular mortality.

Authors:  Marte K R Kjøllesdal; Inger Ariansen; Laust H Mortensen; Øyvind Næss
Journal:  Open Heart       Date:  2017-08-08
  1 in total

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