| Literature DB >> 10752605 |
W J van Berkel1, R H van den Heuvel, C Versluis, A J Heck.
Abstract
Well-resolved ion signals of intact large protein assemblies, with molecular masses extending above one million Dalton, have been detected and mass analyzed using electrospray ionization mass spectrometry, with an uncertainty in mass of <0.2%. The mass spectral data seem to reflect known solution-phase behavior of the studied protein assembly and have therefore been directly used to probe the protein assembly topology and stability as a function of ionic strength and pH.Mesh:
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Year: 2000 PMID: 10752605 PMCID: PMC2144579 DOI: 10.1110/ps.9.3.435
Source DB: PubMed Journal: Protein Sci ISSN: 0961-8368 Impact factor: 6.725