M A Meyer1, C A Nathan. 1. Department of Neurology, University of Missouri School of Medicine, Columbia 65212, USA. MeyerMA@health.missouri.edu
Abstract
PURPOSE: The authors examined the delayed effects of external beam radiation on the metabolism of intravertebral marrow cavities. MATERIALS AND METHODS: Two neurologically normal persons who had completed a full course of external beam radiotherapy for squamous cell carcinoma of the head and neck had positron emission tomography (PET) scans with F-18 fluorodeoxyglucose (FDG) to identify residual neoplasm. RESULTS: Abnormally low uptake of F-18 FDG was noted within the central marrow cavities of the cervical vertebral bodies in both cases. CONCLUSIONS: Diminished metabolic activity within irradiated marrow can be revealed by F-18 FDG PET imaging techniques. Further correlative MRI PET studies are needed to determine if this postradiation phenomenon is related to fatty infiltration of the marrow cavity.
PURPOSE: The authors examined the delayed effects of external beam radiation on the metabolism of intravertebral marrow cavities. MATERIALS AND METHODS: Two neurologically normal persons who had completed a full course of external beam radiotherapy for squamous cell carcinoma of the head and neck had positron emission tomography (PET) scans with F-18fluorodeoxyglucose (FDG) to identify residual neoplasm. RESULTS: Abnormally low uptake of F-18FDG was noted within the central marrow cavities of the cervical vertebral bodies in both cases. CONCLUSIONS: Diminished metabolic activity within irradiated marrow can be revealed by F-18FDG PET imaging techniques. Further correlative MRI PET studies are needed to determine if this postradiation phenomenon is related to fatty infiltration of the marrow cavity.
Authors: Toshiki Kazama; Nancy Swanston; Donald A Podoloff; Homer A Macapinlac Journal: Eur J Nucl Med Mol Imaging Date: 2005-08-31 Impact factor: 9.236
Authors: Marina S Kartachova; Renato A Valdés Olmos; Rick L M Haas; Frank J P Hoebers; Michiel W van den Brekel; Nico van Zandwijk; Marcel van Herk; Marcel Verheij Journal: Eur J Nucl Med Mol Imaging Date: 2006-04-04 Impact factor: 9.236