Literature DB >> 10750756

Anterior mitral leaflet prolapse as a primary cause of pure rheumatic mitral insufficiency.

A Kalangos1, M Beghetti, D Vala, E Jaeggi, G Kaya, V Karpuz, N Murith, B Faidutti.   

Abstract

BACKGROUND: This study was designed to revise the mechanisms and repair techniques of anterior mitral leaflet prolapse observed during the correction of pure rheumatic mitral regurgitation in children.
METHODS: From March 1993 to May 1998, 36 children suffering from pure rheumatic mitral regurgitation due to anterior leaflet prolapse underwent mitral valve repair. The mean age was 12.5 years (range, 6 to 16 years). Anterior leaflet prolapse was due to chordal elongation in 25 patients (group A), chordal rupture in 6 patients (group B), and retraction of anterior secondary chordae tendineae, creating a V-shaped deformity in the middle of the anterior leaflet, thus moving the free edge of the anterior leaflet away from the coaptation plane, in 5 patients (group C). Chordal shortening, transposition, and resection of anterior secondary chordae tendineae were used to correct anterior leaflet prolapse according to the predominantly responsible mechanism.
RESULTS: All patients were available for clinical follow-up, which ranged from 6 months to 5 years (mean follow-up, 3 years). Echocardiographic studies were obtained until the 3rd postoperative month, and all patients showed significant improvement in their left ventricular and atrial dimensions. There was one late death related to endocarditis. Two patients in group C who had mitral valve repair underwent mitral valve replacement on the 19th and 24th postoperative months, respectively, because of failure of mitral valve repair.
CONCLUSIONS: Mitral valve repair for pure mitral regurgitation due to rheumatic anterior leaflet prolapse can be performed safely for all types of mechanisms. Although the techniques we used provide stable short-term results in each of these groups, midterm results are better in groups A and B, where tissue thickening is less important, recurrences of rheumatic carditis are lower, and the interval between the first rheumatic attack and the surgical procedure is shorter than in group C.

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Year:  2000        PMID: 10750756     DOI: 10.1016/s0003-4975(99)01396-x

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  4 in total

Review 1.  World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease--an evidence-based guideline.

Authors:  Bo Reményi; Nigel Wilson; Andrew Steer; Beatriz Ferreira; Joseph Kado; Krishna Kumar; John Lawrenson; Graeme Maguire; Eloi Marijon; Mariana Mirabel; Ana Olga Mocumbi; Cleonice Mota; John Paar; Anita Saxena; Janet Scheel; John Stirling; Satupaitea Viali; Vijayalakshmi I Balekundri; Gavin Wheaton; Liesl Zühlke; Jonathan Carapetis
Journal:  Nat Rev Cardiol       Date:  2012-02-28       Impact factor: 32.419

2.  Mitral valve repair in children with rheumatic heart disease.

Authors:  Srirup Chatterjee; Nikhil Bansal; Rajarshi Ghosh; Lakshmi Kumari Sankhyan; Sujoy Chatterjee; Santosh Pandey; Satyajit Bose
Journal:  Indian J Thorac Cardiovasc Surg       Date:  2020-03-25

3.  Screening for subclinical rheumatic heart disease: addressing borderline disease in a real-world setting.

Authors:  Luke D Hunter; Alfonso J K Pecoraro; Anton F Doubell; Mark J Monaghan; Guy W Lloyd; Carl J Lombard; Philip G Herbst
Journal:  Eur Heart J Open       Date:  2021-12-27

4.  Systolic aortic regurgitation in rheumatic carditis: Mechanistic insight by Doppler echocardiography.

Authors:  Jagdish C Mohan; Vishwas Mohan; Madhu Shukla; Arvind Sethi
Journal:  Indian Heart J       Date:  2017-08-24
  4 in total

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