| Literature DB >> 10750497 |
Abstract
A novel, one-pot ring-expansion procedure was developed using Me3S(O)I, NaH, and Sc(OTf)3. The scope and limitations were briefly examined, and a tentative mechanism was proposed. Application of the methodology to known cyclobutanone 1 provided the corresponding cyclopentanone, which was successfully advanced to (+)-carbovir and (+)-aristeromycin.Entities:
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Year: 2000 PMID： 10750497 DOI： 10.1021/jo9919759
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354