| Literature DB >> 107503 |
J A Deans, E D Dennis, S Cohen.
Abstract
The antigenic composition of sequential erythrocytic stages of Plasmodium knowlesi has been compared by crossed immuno-electrophoresis using a pool of immune rhesus monkey antiserum. Eleven major parasite antigens have been identified; 9 are stage-independent, and 2 stage-dependent. Differences in the relative amount of the stage-independent antigens have been demonstrated and quantified. The distribution of antigens between parasites and schizont and infected red cell membranes has been examined. Only 6 of the 11 parasite antigens were exhibited by a schizont membrane preparation, all these antigens were also expressed by the intracellular parasite. Antigens exclusive to the schizont membrane were not demonstrated.Entities:
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Year: 1978 PMID: 107503 DOI: 10.1017/s0031182000050290
Source DB: PubMed Journal: Parasitology ISSN: 0031-1820 Impact factor: 3.234