Literature DB >> 10746869

The use of ebastine, a mast cell blocker, for treatment of oligozoospermia.

S Matsuki1, I Sasagawa, Y Suzuki, H Yazawa, T Tateno, T Hashimoto, T Nakada, H Saito, M Hiroi.   

Abstract

The effect of mast cell blocker (ebastine) on semen quality was evaluated in 15 idiopathic oligozoospermic males. Ten milligrams/day of ebastine was administered orally for 3 months. Nine cases (66.7%) showed definite improvement in the semen quality. The wives of 3 patients (20%) became pregnant within 6 months of the initial treatment. It would appear that mast cell blocker (ebastine) significantly improves semen quality in men with idiopathic oligozoospermia.

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Year:  2000        PMID: 10746869     DOI: 10.1080/014850100262290

Source DB:  PubMed          Journal:  Arch Androl        ISSN: 0148-5016


  2 in total

Review 1.  Management strategies for male factor infertility.

Authors:  Gerhard Haidl
Journal:  Drugs       Date:  2002       Impact factor: 9.546

2.  Effect of ketotifen fumarate on experimental autoimmune orchitis and torsion of the spermatic cord.

Authors:  Diego Moreno; Cristian M Sobarzo; Livia Lustig; Marcelo G Rodríguez Peña; Vanesa Anabella Guazzone
Journal:  Asian J Androl       Date:  2020 Jan-Feb       Impact factor: 3.285

  2 in total

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