Literature DB >> 10745102

Characterization of Trypanozoon isolates using a repeated coding sequence and microsatellite markers.

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Abstract

Genetic variation of microsatellite loci is a widely used method for linkage analysis, individual identification or inter-population studies. Here we analyse a repeated DNA coding sequence and eleven new microsatellites identified within the Trypanosoma (Trypanozoon) brucei genome. Ninety-seven isolates belonging to the five species and subspecies Trypanosoma evansi, T. equiperdum, T. brucei brucei, T. b. rhodesiense and T. b. gambiense were compared regarding the genetic patterns of these markers. The results reveal a great heterogeneity of the genotypes related to the repeated coding sequence and five microsatellites, some of which show a high degree of polymorphism. This allows us to define group-specific genotypes or alleles; in particular, we show that one specific pattern clearly segregates the human pathogen T. b. gambiense group 1.

Entities:  

Year:  2000        PMID： 10745102

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


  8 in total

1.  Phylogeography and taxonomy of Trypanosoma brucei.

Authors:  Oliver Balmer; Jon S Beadell; Wendy Gibson; Adalgisa Caccone
Journal:  PLoS Negl Trop Dis       Date:  2011-02-08

2.  Characterization of di-, tri-, and tetranucleotide microsatellite markers with perfect repeats for Trypanosoma brucei and related species.

Authors:  Oliver Balmer; Christopher Palma; Annette Macleod; Adalgisa Caccone
Journal:  Mol Ecol Notes       Date:  2006-06

3.  Molecular characterization and classification of Trypanosoma spp. Venezuelan isolates based on microsatellite markers and kinetoplast maxicircle genes.

Authors:  E Sánchez; T Perrone; G Recchimuzzi; I Cardozo; N Biteau; P M Aso; A Mijares; T Baltz; D Berthier; L Balzano-Nogueira; M I Gonzatti
Journal:  Parasit Vectors       Date:  2015-10-15       Impact factor: 3.876

4.  Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model.

Authors:  Frédéric-Antoine Dauchy; Mélanie Bonhivers; Nicolas Landrein; Denis Dacheux; Pierrette Courtois; Florian Lauruol; Sylvie Daulouède; Philippe Vincendeau; Derrick R Robinson
Journal:  PLoS Negl Trop Dis       Date:  2016-11-17

5.  Description of the first sleeping sickness case diagnosed in Burkina Faso since two decades.

Authors:  Emilie Dama; Aboubacar Drabo; Jacques Kaboré; Elie Ouédraogo; Bamoro Coulibaly; Hamidou Ilboudo; Justin Kaboré; Charlie Franck Compaoré; Hassane Sakandé; Micheline Ouédraogo; Jean-Baptiste Rayaissé; Fabrice Courtin; Philippe Solano; François Drabo; Vincent Jamonneau
Journal:  PLoS Negl Trop Dis       Date:  2018-08-20

6.  Murine Models for Trypanosoma brucei gambiense disease progression--from silent to chronic infections and early brain tropism.

Authors:  Christiane Giroud; Florence Ottones; Virginie Coustou; Denis Dacheux; Nicolas Biteau; Benjamin Miezan; Nick Van Reet; Mark Carrington; Felix Doua; Théo Baltz
Journal:  PLoS Negl Trop Dis       Date:  2009-09-01

7.  Population genetic structure and temporal stability among Trypanosoma brucei rhodesiense isolates in Uganda.

Authors:  Charles D Kato; Vincent P Alibu; Ann Nanteza; Claire M Mugasa; Enock Matovu
Journal:  Parasit Vectors       Date:  2016-05-03       Impact factor: 3.876

8.  Relationship between Trypanosoma brucei rhodesiense genetic diversity and clinical spectrum among sleeping sickness patients in Uganda.

Authors:  Charles D Kato; Claire M Mugasa; Ann Nanteza; Enock Matovu; Vincent P Alibu
Journal:  BMC Res Notes       Date:  2017-10-27
  8 in total

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