Literature DB >> 10744999

The Sir proteins of Saccharomyces cerevisiae: mediators of transcriptional silencing and much more.

M R Gartenberg1.   

Abstract

The Sir2, Sir3, and Sir4 proteins of the yeast Saccharomyces cerevisiae elicit transcriptional silencing by forming repressive chromatin structures that are confined to specific chromosomal domains. Recent discoveries establish new and unexpected roles for the proteins in seemingly unrelated arenas of chromosome biology, including double-strand break repair, structure and function of the nucleolus, aging, cell cycle regulation, and checkpoint control.

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Year:  2000        PMID： 10744999     DOI： 10.1016/s1369-5274(00)00064-3

Source DB:  PubMed          Journal:  Curr Opin Microbiol        ISSN： 1369-5274            Impact factor:   7.934


  32 in total

1.  Polycomb group repression reduces DNA accessibility.

Authors:  D P Fitzgerald; W Bender
Journal:  Mol Cell Biol       Date:  2001-10       Impact factor: 4.272

2.  SIR2-induced inviability is suppressed by histone H4 overexpression.

Authors:  Mirela Matecic; Shelagh Stuart; Scott G Holmes
Journal:  Genetics       Date:  2002-10       Impact factor: 4.562

Review 3.  The different (sur)faces of Rap1p.

Authors:  B Piña; J Fernández-Larrea; N García-Reyero; F-Z Idrissi
Journal:  Mol Genet Genomics       Date:  2003-01-25       Impact factor: 3.291

4.  Importance of the Sir3 N terminus and its acetylation for yeast transcriptional silencing.

Authors:  Xiaorong Wang; Jessica J Connelly; Chia-Lin Wang; Rolf Sternglanz
Journal:  Genetics       Date:  2004-09       Impact factor: 4.562

5.  Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing.

Authors:  Shengbing Huang; Hui Zhou; David Katzmann; Mark Hochstrasser; Elena Atanasova; Zhiguo Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-12       Impact factor: 11.205

6.  Suppressor analysis of the mpt5/htr1/uth4/puf5 deletion in Saccharomyces cerevisiae.

Authors:  Kentaro Ohkuni; Yoshiko Kikuchi; Kazuhiro Hara; Tsuya Taneda; Naoyuki Hayashi; Akihiko Kikuchi
Journal:  Mol Genet Genomics       Date:  2005-11-17       Impact factor: 3.291

7.  Identification of a small molecule inhibitor of Sir2p.

Authors:  A Bedalov; T Gatbonton; W P Irvine; D E Gottschling; J A Simon
Journal:  Proc Natl Acad Sci U S A       Date:  2001-12-18       Impact factor: 11.205

Review 8.  Nucleosome positioning in Saccharomyces cerevisiae.

Authors:  An Jansen; Kevin J Verstrepen
Journal:  Microbiol Mol Biol Rev       Date:  2011-06       Impact factor: 11.056

9.  Esc1, a nuclear periphery protein required for Sir4-based plasmid anchoring and partitioning.

Authors:  Erik D Andrulis; David C Zappulla; Athar Ansari; Severine Perrod; Catherine V Laiosa; Marc R Gartenberg; Rolf Sternglanz
Journal:  Mol Cell Biol       Date:  2002-12       Impact factor: 4.272

10.  Liver-specific deletion of histone deacetylase 3 disrupts metabolic transcriptional networks.

Authors:  Sarah K Knutson; Brenda J Chyla; Joseph M Amann; Srividya Bhaskara; Stacey S Huppert; Scott W Hiebert
Journal:  EMBO J       Date:  2008-03-20       Impact factor: 11.598
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