Literature DB >> 10743949

(1,4-Benzothiazinyloxy)alkylpiperazine derivatives as potential antihypertensive agents.

V Cecchetti1, F Schiaffella, O Tabarrini, A Fravolini.   

Abstract

A series of compounds having a piperazine moiety variously linked to the benzothiazine nucleus were synthesized and evaluated for their in vitro alpha-adrenoceptor affinity by radioligand receptor binding assays. Some compounds bearing a oxyalkyl-(2-methoxyphenyl)piperazine side chain were good alpha1-adrenoreceptor ligands.

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Year:  2000        PMID： 10743949     DOI： 10.1016/s0960-894x(00)00016-0

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  3 in total

1.  Divergent label-free cell phenotypic pharmacology of ligands at the overexpressed β₂-adrenergic receptors.

Authors:  Ann M Ferrie; Haiyan Sun; Natalya Zaytseva; Ye Fang
Journal:  Sci Rep       Date:  2014-01-23       Impact factor: 4.379

2.  4-Azatricyclo[5.2.2.02,6]undecane-3,5,8-triones as potential pharmacological agents.

Authors:  Jerzy Kossakowski; Anna Bielenica; Barbara Mirosław; Anna E Kozioł; Izabela Dybała; Marta Struga
Journal:  Molecules       Date:  2008-08-06       Impact factor: 4.411

3.  Sulfonic acid functionalized nano-γ-Al2O3: a new, efficient, and reusable catalyst for synthesis of 3-substituted-2H-1,4-benzothiazines.

Authors:  Wei Lin Li; Shuan Bao Tian; Feng Zhu
Journal:  ScientificWorldJournal       Date:  2013-07-14
  3 in total

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