Literature DB >> 10743623

Further evidence for a link between melarsoprol resistance and P2 transporter function in African trypanosomes.

H P de Koning1, A MacLeod, M P Barrett, B Cover, S M Jarvis.   

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Year:  2000        PMID： 10743623     DOI： 10.1016/s0166-6851(99)00206-6

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN： 0166-6851            Impact factor:   1.759


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  20 in total

1.  Trypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns.

Authors:  Christopher P Ward; Pui Ee Wong; Richard J Burchmore; Harry P de Koning; Michael P Barrett
Journal:  Antimicrob Agents Chemother       Date:  2011-03-14       Impact factor: 5.191

2.  The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.

Authors:  Harry P de Koning; Laura F Anderson; Mhairi Stewart; Richard J S Burchmore; Lynsey J M Wallace; Michael P Barrett
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

3.  The Chemical Characterization of Nigerian Propolis samples and Their Activity Against Trypanosoma brucei.

Authors:  Ruwida Omar; John O Igoli; Tong Zhang; Alexander I Gray; Godwin U Ebiloma; Carol J Clements; James Fearnley; RuAngeli Edrada Ebel; Tim Paget; Harry P de Koning; David G Watson
Journal:  Sci Rep       Date:  2017-04-19       Impact factor: 4.379

4.  Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal.

Authors:  Anne J N Kazibwe; Barbara Nerima; Harry P de Koning; Pascal Mäser; Michael P Barrett; Enock Matovu
Journal:  PLoS Negl Trop Dis       Date:  2009-09-29

Review 5.  Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story.

Authors:  Nicola Baker; Harry P de Koning; Pascal Mäser; David Horn
Journal:  Trends Parasitol       Date:  2013-01-30

6.  Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.

Authors:  Ali H Alghamdi; Jane C Munday; Gustavo Daniel Campagnaro; Dominik Gurvic; Fredrik Svensson; Chinyere E Okpara; Arvind Kumar; Juan Quintana; Maria Esther Martin Abril; Patrik Milić; Laura Watson; Daniel Paape; Luca Settimo; Anna Dimitriou; Joanna Wielinska; Graeme Smart; Laura F Anderson; Christopher M Woodley; Siu Pui Ying Kelly; Hasan Ms Ibrahim; Fabian Hulpia; Mohammed I Al-Salabi; Anthonius A Eze; Teresa Sprenger; Ibrahim A Teka; Simon Gudin; Simone Weyand; Mark Field; Christophe Dardonville; Richard R Tidwell; Mark Carrington; Paul O'Neill; David W Boykin; Ulrich Zachariae; Harry P De Koning
Journal:  Elife       Date:  2020-08-11       Impact factor: 8.140

7.  Activity of Compounds from Temperate Propolis against Trypanosoma brucei and Leishmania mexicana.

Authors:  Adullah Alotaibi; Godwin U Ebiloma; Roderick Williams; Ibrahim A Alfayez; Manal J Natto; Sameah Alenezi; Weam Siheri; Malik AlQarni; John O Igoli; James Fearnley; Harry P De Koning; David G Watson
Journal:  Molecules       Date:  2021-06-26       Impact factor: 4.411

8.  Cyclic AMP effectors in African trypanosomes revealed by genome-scale RNA interference library screening for resistance to the phosphodiesterase inhibitor CpdA.

Authors:  Matthew K Gould; Sabine Bachmaier; Juma A M Ali; Sam Alsford; Daniel N A Tagoe; Jane C Munday; Achim C Schnaufer; David Horn; Michael Boshart; Harry P de Koning
Journal:  Antimicrob Agents Chemother       Date:  2013-07-22       Impact factor: 5.191

9.  Chemical and Antimicrobial Profiling of Propolis from Different Regions within Libya.

Authors:  Weam Siheri; Tong Zhang; Godwin Unekwuojo Ebiloma; Marco Biddau; Nicola Woods; Muattaz Yassein Hussain; Carol J Clements; James Fearnley; RuAngelie Edrada Ebel; Timothy Paget; Sylke Muller; Katharine C Carter; Valerie A Ferro; Harry P De Koning; David G Watson
Journal:  PLoS One       Date:  2016-05-19       Impact factor: 3.240

10.  European propolis is highly active against trypanosomatids including Crithidia fasciculata.

Authors:  Abdullah Alotaibi; Godwin U Ebiloma; Roderick Williams; Samya Alenezi; Anne-Marie Donachie; Selome Guillaume; John O Igoli; James Fearnley; Harry P de Koning; David G Watson
Journal:  Sci Rep       Date:  2019-08-06       Impact factor: 4.379
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