Literature DB >> 10742371

Voiding cystourethrograms and urinary tract infections: how long to wait?

A McDonald1, M Scranton, R Gillespie, V Mahajan, G A Edwards.   

Abstract

OBJECTIVES: Many authorities recommend an interval of at least 3 to 6 weeks after a urinary tract infection (UTI) before performing a voiding cystourethrogram (VCUG). However, such an interval may reduce the likelihood of completing the procedure. This study was performed to investigate whether the length of the interval between a UTI and the performance of the VCUG influences the presence or severity of reflux, and whether it influences the likelihood of actually having the study performed.
DESIGN: We reviewed 352 admissions of children under 10 years old whose discharge diagnoses indicated UTIs. These admissions occurred over a 27-month period between October 1994 and December 1996 at the Children's Hospital of Austin, Texas. We identified 213 patients with confirmed UTIs and no other previously defined urinary tract pathology. These patients were divided into 2 groups according to whether they had a VCUG scheduled to be performed either within 1 week after the diagnosis of a UTI (the early group), or later than 1 week after the diagnosis (the late group). We compared the presence and severity of reflux in the 2 groups as well as the proportion of scheduled VCUGs that were actually performed.
RESULTS: Reflux was present in 19% of the patients studied within 1 week after UTI (95% confidence interval [CI]: 12.9-26.4) and in 18% of those studied after 1 week (95% CI: 6. 7-34.5). This difference was not statistically significant (chi(2) =. 034; DF = 1). However there was a substantial difference between the 2 groups with regard to the number of scheduled VCUGs actually performed. Whereas 100% of the scheduled VCUGs in the early group were performed, only 48% (95% CI: 35.9-60.1) of those scheduled in the late group were performed. This difference is statistically significant (chi(2) = 89.6; DF = 1).
CONCLUSIONS: In the hospitalized children who underwent VCUGs within a week after diagnosis of UTI, the presence of reflux is not significantly different from those studied later. Furthermore, late scheduling of VCUGs resulted in failure to perform the procedure in more than half of the patients. Some of the patients who were not evaluated would be expected to have vesicoureteral reflux and thus be at risk for chronic renal disease. Therefore, the traditional recommendation to perform the VCUG at 3 to 6 weeks after the diagnosis of UTI should be reconsidered, especially for hospitalized children.

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Year:  2000        PMID: 10742371     DOI: 10.1542/peds.105.4.e50

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  14 in total

1.  Voiding cystourethrogram: How much should we be selective?

Authors:  Sibel Yel; Sebahat Tülpar; Ruhan Düşünsel; Hakan Muammer Poyrazoğlu; İsmail Dursun; Ümmühan Abdülrezzak; Zübeyde Gündüz; Kenan Yılmaz; Funda Baştuğ
Journal:  Turk J Urol       Date:  2017-01-27

2.  The accuracy and health risks of a voiding cystourethrogram after a febrile urinary tract infection.

Authors:  John David Spencer; Carlton M Bates; John D Mahan; Mary-Lynn Niland; Shannon R Staker; David S Hains; Andrew L Schwaderer
Journal:  J Pediatr Urol       Date:  2010-12-03       Impact factor: 1.830

Review 3.  Diagnosis and management of pediatric urinary tract infections.

Authors:  Joseph J Zorc; Darcie A Kiddoo; Kathy N Shaw
Journal:  Clin Microbiol Rev       Date:  2005-04       Impact factor: 26.132

4.  Timing of voiding cystourethrography in infants with first time urinary infection.

Authors:  Dimitrios Doganis; Mersini Mavrikou; Dimitrios Delis; Lela Stamoyannou; Konstantinos Siafas; Konstantinos Sinaniotis
Journal:  Pediatr Nephrol       Date:  2008-10-14       Impact factor: 3.714

Review 5.  A guideline for the inpatient care of children with pyelonephritis.

Authors:  Aftab S Chishti; Erich C Maul; Rubén J Nazario; Jeffrey S Bennett; Stefan G Kiessling
Journal:  Ann Saudi Med       Date:  2010 Sep-Oct       Impact factor: 1.526

6.  [Diagnostics and therapy of urinary tract infections].

Authors:  R Beetz; F Wagenlehner
Journal:  Urologe A       Date:  2013-01       Impact factor: 0.639

7.  Urinary tract infection in the newborn: clinical and radio imaging studies.

Authors:  José B López Sastre; Antonio Ramos Aparicio; Gil D Coto Cotallo; Belén Fernández Colomer; Manuel Crespo Hernández
Journal:  Pediatr Nephrol       Date:  2007-07-31       Impact factor: 3.714

8.  Urinary Tract Infection in Boys Less Than Five Years of Age: A General Pediatric Perspective.

Authors:  Hany M Nadi; Yasser A F Shalan; Hanan Y A Al-Qatan; Saad Alotaibi
Journal:  Kuwait Med J       Date:  2006-09       Impact factor: 0.076

9.  The RIVUR trial: profile and baseline clinical associations of children with vesicoureteral reflux.

Authors:  Myra A Carpenter; Alejandro Hoberman; Tej K Mattoo; Ranjiv Mathews; Ron Keren; Russell W Chesney; Marva Moxey-Mims; Saul P Greenfield
Journal:  Pediatrics       Date:  2013-06-10       Impact factor: 7.124

10.  Significance of Sonographically Demonstrated Ureteral Dilatation in Evaluation of Vesicoureteral Reflux Verified with Voiding Urosonography in Children with Urinary Tract Infection.

Authors:  Aladin Carovac; Sandra Vegar Zubovic; Marklena Carovac; Irmina Sefic Pasic
Journal:  Acta Inform Med       Date:  2015-10-05
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