Literature DB >> 10742186

Metal ions in ribozyme folding and catalysis.

R Hanna1, J A Doudna.   

Abstract

Current research is reshaping basic theories regarding the roles of metal ions in ribozyme function. No longer viewed as strict metalloenzymes, some ribozymes can access alternative catalytic mechanisms depending on the identity and availability of metal ions. Similarly, reaction conditions can allow different folding pathways to predominate, with divalent cations sometimes playing opposing roles.

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Year:  2000        PMID： 10742186     DOI： 10.1016/s1367-5931(99)00071-x

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  24 in total

Review 1.  Recent advances in the elucidation of the mechanisms of action of ribozymes.

Authors:  Y Takagi; M Warashina; W J Stec; K Yoshinari; K Taira
Journal:  Nucleic Acids Res       Date:  2001-05-01       Impact factor: 16.971

2.  Evidence for a polynuclear metal ion binding site in the catalytic domain of ribonuclease P RNA.

Authors:  Eric L Christian; Nicholas M Kaye; Michael E Harris
Journal:  EMBO J       Date:  2002-05-01       Impact factor: 11.598

3.  Characterization of RNA determinants recognized by the arginine- and proline-rich region of Us11, a herpes simplex virus type 1-encoded double-stranded RNA binding protein that prevents PKR activation.

Authors:  David Khoo; Cesar Perez; Ian Mohr
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

4.  Outersphere and innersphere coordinated metal ions in an aminoacyl-tRNA synthetase ribozyme.

Authors:  Hirohide Saito; Hiroaki Suga
Journal:  Nucleic Acids Res       Date:  2002-12-01       Impact factor: 16.971

Review 5.  Biological inorganic chemistry at the beginning of the 21st century.

Authors:  Harry B Gray
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-25       Impact factor: 11.205

6.  Microenvironment analysis and identification of magnesium binding sites in RNA.

Authors:  D Rey Banatao; Russ B Altman; Teri E Klein
Journal:  Nucleic Acids Res       Date:  2003-08-01       Impact factor: 16.971

7.  Entropy-driven folding of an RNA helical junction: an isothermal titration calorimetric analysis of the hammerhead ribozyme.

Authors:  Peter J Mikulecky; Jennifer C Takach; Andrew L Feig
Journal:  Biochemistry       Date:  2004-05-18       Impact factor: 3.162

8.  Effects of background anionic compounds on the activity of the hammerhead ribozyme in Mg(2+)-unsaturated solutions.

Authors:  Shu-ichi Nakano; Yuichi Kitagawa; Daisuke Miyoshi; Naoki Sugimoto
Journal:  J Biol Inorg Chem       Date:  2015-07-29       Impact factor: 3.358

9.  Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs.

Authors:  Alexander Serganov; Yu-Ren Yuan; Olga Pikovskaya; Anna Polonskaia; Lucy Malinina; Anh Tuân Phan; Claudia Hobartner; Ronald Micura; Ronald R Breaker; Dinshaw J Patel
Journal:  Chem Biol       Date:  2004-12

10.  A united residue force-field for calcium-protein interactions.

Authors:  Mey Khalili; Jeffrey A Saunders; Adam Liwo; Stanislaw Ołdziej; Harold A Scheraga
Journal:  Protein Sci       Date:  2004-10       Impact factor: 6.725
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