| Literature DB >> 10741563 |
P A Coates1, P Grundt, E S Robinson, D J Nutt, R Tyacke, A L Hudson, J W Lewis, S M Husbands.
Abstract
An irreversible ligand (7) has been prepared based on the selective I2 ligand 2-BFI. Compound 7 displayed high affinity and selectivity for I2-sites and has been shown to irreversibly bind to these sites in rat brain. Compound 7 should, therefore, prove an invaluable tool for the further elucidation of I2-site function.Entities:
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Year: 2000 PMID： 10741563 DOI： 10.1016/s0960-894x(00)00062-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823