| Literature DB >> 10741195 |
B S Ooi1, D C Nyam, C Cheng, K C Tan, W H Koo, K S Lee.
Abstract
We report a case of locally advanced carcinoma of the rectum invading the bladder and prostate in a young man treated initially with neoadjuvant chemoradiotherapy. This was followed by an en bloc resection of the tumour, partial cystectomy and prostatectomy and an abdominal perineal resection. The urinary bladder was reconstructed and a new bladder neck reimplanted into the proximal urethra where the sphincter had been preserved. There was extensive radiation changes to the perineal skin where a wide excision had been performed. The pelvic defect was reconstructed with a pedicled transpelvic rectus abdominis myocutaneous flap. The patient recovered uneventfully and remains well with no clinical evidence of recurrence 18 months post-operatively. In very selected cases there is a definite role for neoadjuvant therapy and enbloc resection of the tumour followed by reconstruction of the perineum.Entities:
Mesh:
Year: 1999 PMID: 10741195
Source DB: PubMed Journal: Singapore Med J ISSN: 0037-5675 Impact factor: 1.858