Literature DB >> 10739908

Severe heart valve calcification in a young patient with Werner syndrome.

H Grubitzsch1, S Beholz, H G Wollert, L Eckel.   

Abstract

Werner syndrome is a rare autosomal recessive disorder characterized by the appearance of premature aging. We report on severe aortic and mitral valve calcification in an 18-year-old girl, necessitating double valve replacement. These special cardiovascular findings are discussed with regard to diagnosis and treatment.

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Mesh：

Year:  2000        PMID： 10739908     DOI： 10.1016/s1054-8807(99)00036-8

Source DB:  PubMed          Journal:  Cardiovasc Pathol        ISSN： 1054-8807            Impact factor:   2.185


  3 in total

Review 1.  Calcific aortic valve stenosis: methods, models, and mechanisms.

Authors:  Jordan D Miller; Robert M Weiss; Donald D Heistad
Journal:  Circ Res       Date:  2011-05-27       Impact factor: 17.367

2.  Improvement of aortic valve stenosis by ApoA-I mimetic therapy is associated with decreased aortic root and valve remodelling in mice.

Authors:  J Trapeaux; D Busseuil; Y Shi; S Nobari; D Shustik; M Mecteau; I El-Hamamsy; M Lebel; R Mongrain; E Rhéaume; J-C Tardif
Journal:  Br J Pharmacol       Date:  2013-08       Impact factor: 8.739

3.  Aortic valve replacement with annular patch enlargement for a patient with Werner's syndrome and severe aortic stenosis.

Authors:  Kazuma Handa; Shinya Fukui; Yukitoshi Shirakawa; Tomohiko Sakamoto; Mutsunori Kitahara; Yumi Kakizawa; Hiroyuki Nishi
Journal:  J Cardiothorac Surg       Date:  2020-07-17       Impact factor: 1.637
  3 in total

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