Literature DB >> 10735087

Clinical experience with flow cytometric separation of human X- and Y-chromosome bearing sperm.

E F Fugger1.   

Abstract

Numerous methods to separate human X- and Y-bearing sperm have been reported with unconfirmed separation after DNA analysis and inconsistent birth results. Successful flow cytometric separation of sperm resulting in alteration of the sex ratio of young born has been demonstrated in several animal species. Flow cytometric separation of human X- and Y-bearing sperm (MicroSort) has been confirmed after DNA analysis by fluorescence in situ hybridization (FISH). Pregnancies and births have resulted from the use of MicroSort after intrauterine insemination (IUI), in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI).

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Year:  1999        PMID： 10735087     DOI： 10.1016/s0093-691x(99)00228-9

Source DB:  PubMed          Journal:  Theriogenology        ISSN： 0093-691X            Impact factor:   2.740


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6.  The effectiveness of flow cytometric sorting of human sperm (MicroSort®) for influencing a child's sex.

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  6 in total

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