Literature DB >> 10734688

[A multicenter study of the antimicrobial effect of Macmiror and Macmiror Complex in the treatment of vaginal infections].

I Karag'ozov, E Shopova, K Poriazov, I Abaliev, I Kozovski, R Ianeva, S Drenska, P Vasileva, S Bozhinova, I Popov, S Stoĭkov.   

Abstract

UNLABELLED: The aim of the present multicentre study was to examine the therapeutic possibilities of the wide-spectrum medicament MACMIROR & MACMIROR COMPLEX for the treatment of the vaginal infections.
MATERIALS AND METHODS: The study included 159 nonpregnant women among 15 and 54 years (middle age 35.6) with different by kind and intensity colpitis complaints. The following microbiological characteristic was established: in 26 cases Gardnerella vaginalis, in 46 Candida spp., and in the rest 87-mixed aerobic bacterial flora, with a combination of Gardnerella, yeast and Trichomonas. The treatment of the patients was done in combined scheme: peroral and vaginal administration, simultaneously with local treatment of the partner. The control examination was performed bistagely: on 7-10 day and on 30-40 day.
RESULTS: The good clinical and microbiological influence of the treated patients was established, for the first control examination the effect was found in 88.1% and 86.8% and for the second--respectively in 81.1% and 82.4%.
CONCLUSIONS: The received results give us a cause to approve, that the combination "Nifuratel and Nystatin" (Macmiror & Macmimor complex) has the good possibilities to influence the mixed forms of vaginal infection.

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Year:  1999        PMID: 10734688

Source DB:  PubMed          Journal:  Akush Ginekol (Sofiia)        ISSN: 0324-0959


  1 in total

1.  An improved HPLC method for determination of nifuratel in human plasma and its application to pharmacokinetics studies.

Authors:  Xiao-Li Li; Bao-Ying Li; Mei-Yuan Ni; Ben-Jie Wang; Rui-Chen Guo
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2007 Apr-Jun       Impact factor: 2.441

  1 in total

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