Literature DB >> 10733476

Assessing the prevalence of hand osteoarthritis in epidemiological studies. The reliability of a radiological hand scale.

S Kessler1, P Dieppe, J Fuchs, T Stürmer, K P Günther.   

Abstract

OBJECTIVE: The hands are often involved in the osteoarthritic disease process. A radiological grading scale is presented, derived from a published atlas, to assess the prevalence of hand osteoarthritis (OA) involvement in clinical and epidemiological studies and its reproducibility is studied.
METHODS: This hand scale is based on the radiological feature "joint space narrowing", which represents the macromorphological process of cartilage loss. Osteophytes and sclerosis are less important unless seen in conjuction with joint space narrowing. Nine individual joints per hand (four proximal interphalangeal joints (PIP), four distal interphalangeal joints (DIP), first carpometacarpal joint (CMC-1)) are scored dichotomously for the presence of OA. To save time and to increase reliability a severity grading of radiological features is not performed. To determine inter-rater and intra-rater reliability of the individual joints and the presence of OA in two separate joint groups (>/= 2 PIP or DIP and at least one CMC-1, used to define "generalised OA" in the ongoing Ulm Osteoarthritis Study) 50 pairs of anteroposterior hand radiographs were read by two investigators twice within one month. The kappa coefficient was calculated to quantify the strength of associations.
RESULTS: On average five minutes were needed to score one hand radiograph. Both raters were able to reproduce their own readings in all individual joints and for the presence of OA in two separate joint groups after one month. Reliability was highest for the PIP joints (kappa: 0.56-1. 00) it was slightly lower for the DIP joints (0.38-0.87), for the CMC-1 joints (0.58-0.69) and for OA in two separate joint groups (0. 54). The values for inter-rater agreement were good as well, kappa coefficients ranged from 0.52 to 0.92.
CONCLUSION: This grading scale was shown to be reliable within and between readers for all the individual joints as well as for the presence of OA in two separate joint groups. Scoring a limited number of joints dichotomously makes this scale efficient and therefore useful for clinical and epidemiological trials, when dealing with large patient samples.

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Year:  2000        PMID: 10733476      PMCID: PMC1753111          DOI: 10.1136/ard.59.4.289

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


  10 in total

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3.  Epidemiology of osteoarthritis: Zoetermeer survey. Comparison of radiological osteoarthritis in a Dutch population with that in 10 other populations.

Authors:  J L van Saase; L K van Romunde; A Cats; J P Vandenbroucke; H A Valkenburg
Journal:  Ann Rheum Dis       Date:  1989-04       Impact factor: 19.103

4.  Association of hand and knee osteoarthritis: evidence for a polyarticular disease subset.

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5.  Serum cholesterol and osteoarthritis. The baseline examination of the Ulm Osteoarthritis Study.

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Review 6.  Epidemiology of osteoarthritis: current concepts and new insights.

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Journal:  J Rheumatol Suppl       Date:  1991-02

7.  Reliability of new indices of radiographic osteoarthritis of the hand and hip and lumbar disc degeneration.

Authors:  N E Lane; M C Nevitt; H K Genant; M C Hochberg
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8.  Atlas of individual radiographic features in osteoarthritis.

Authors:  R D Altman; M Hochberg; W A Murphy; F Wolfe; M Lequesne
Journal:  Osteoarthritis Cartilage       Date:  1995-09       Impact factor: 6.576

9.  Patterns of joint involvement in osteoarthritis of the hand: the Chingford Study.

Authors:  P Egger; C Cooper; D J Hart; D V Doyle; D Coggon; T D Spector
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10.  Defining osteoarthritis of the hand for epidemiological studies: the Chingford Study.

Authors:  D Hart; T Spector; P Egger; D Coggon; C Cooper
Journal:  Ann Rheum Dis       Date:  1994-04       Impact factor: 19.103

  10 in total
  7 in total

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2.  Reproducibility and sensitivity to change of four scoring methods for the radiological assessment of osteoarthritis of the hand.

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3.  Hand X-ray examination in two planes is not required for radiographic assessment of hand osteoarthritis.

Authors:  Kevin Staats; Ilse-Gerlinde Sunk; Claudia Weidekamm; Andreas Kerschbaumer; Manuel Bécède; Gabriela Supp; Tanja Stamm; Reinhard Windhager; Josef S Smolen; Klaus Bobacz
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4.  Severity and extent of osteoarthritis and low grade systemic inflammation as assessed by high sensitivity C reactive protein.

Authors:  T Stürmer; H Brenner; W Koenig; K-P Günther
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5.  First carpometacarpal and interphalangeal osteoarthritis of the hand in patients with advanced hip or knee OA. Are there differences in the aetiology?

Authors:  S Kessler; J Stöve; W Puhl; T Stürmer
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6.  Research in hand osteoarthritis: time for reappraisal and demand for new strategies. An opinion paper.

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Journal:  Ann Rheum Dis       Date:  2007-03-14       Impact factor: 19.103

7.  Dorso-ventral osteophytes of interphalangeal joints correlate with cartilage damage and synovial inflammation in hand osteoarthritis: a histological/radiographical study.

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  7 in total

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