Literature DB >> 10732739

H19 and IGF-2 allele-specific expression in hepatoblastoma.

J A Ross1, G A Radloff, S M Davies.   

Abstract

Patterns of allele-specific expression of H19 and insulin-like growth factor-2 (IGF-2) were examined in tissue obtained from 30 children diagnosed with hepatoblastoma. All informative tumours demonstrated monoallelic expression of H19. In contrast, variable patterns of allele-specific expression of IGF-2 were seen in tumours from children of different ages.

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Year:  2000        PMID： 10732739      PMCID： PMC2374392          DOI： 10.1054/bjoc.1999.0992

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  22 in total

1.  Genomic imprinting of H19 and insulin-like growth factor-2 in pediatric germ cell tumors.

Authors:  J A Ross; P T Schmidt; J P Perentesis; S M Davies
Journal:  Cancer       Date:  1999-03-15       Impact factor: 6.860

2.  Maintenance of genomic imprinting at the IGF2 locus in hepatoblastoma.

Authors:  S M Davies
Journal:  Cancer Res       Date:  1993-10-15       Impact factor: 12.701

3.  Developmental regulation of genomic imprinting of the IGF2 gene in human liver.

Authors:  S M Davies
Journal:  Cancer Res       Date:  1994-05-15       Impact factor: 12.701

4.  Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumors.

Authors:  R J van Gurp; J W Oosterhuis; V Kalscheuer; E C Mariman; L H Looijenga
Journal:  J Natl Cancer Inst       Date:  1994-07-20       Impact factor: 13.506

5.  Relaxation of imprinted genes in human cancer.

Authors:  S Rainier; L A Johnson; C J Dobry; A J Ping; P E Grundy; A P Feinberg
Journal:  Nature       Date:  1993-04-22       Impact factor: 49.962

6.  Loss of imprinting in hepatoblastoma.

Authors:  S Rainier; C J Dobry; A P Feinberg
Journal:  Cancer Res       Date:  1995-05-01       Impact factor: 12.701

7.  Physical linkage of two mammalian imprinted genes, H19 and insulin-like growth factor 2.

Authors:  S Zemel; M S Bartolomei; S M Tilghman
Journal:  Nat Genet       Date:  1992-09       Impact factor: 38.330

8.  Increased birth weights of National Wilms' Tumor Study patients suggest a growth factor excess.

Authors:  W M Leisenring; N E Breslow; I E Evans; J B Beckwith; M J Coppes; P Grundy
Journal:  Cancer Res       Date:  1994-09-01       Impact factor: 12.701

9.  IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndrome.

Authors:  R Ohlsson; A Nyström; S Pfeifer-Ohlsson; V Töhönen; F Hedborg; P Schofield; F Flam; T J Ekström
Journal:  Nat Genet       Date:  1993-05       Impact factor: 38.330

10.  Promoter-specific IGF2 imprinting status and its plasticity during human liver development.

Authors:  T J Ekström; H Cui; X Li; R Ohlsson
Journal:  Development       Date:  1995-02       Impact factor: 6.868
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  2 in total

1.  Focal overexpression of insulin-like growth factor 2 by hepatocytes and cholangiocytes in viral liver cirrhosis.

Authors:  N Sedlaczek; A Hasilik; P Neuhaus; D Schuppan; H Herbst
Journal:  Br J Cancer       Date:  2003-03-10       Impact factor: 7.640

2.  Loss of imprinting of IGF2 correlates with hypermethylation of the H19 differentially methylated region in hepatoblastoma.

Authors:  S Honda; Y Arai; M Haruta; F Sasaki; M Ohira; H Yamaoka; H Horie; A Nakagawara; E Hiyama; S Todo; Y Kaneko
Journal:  Br J Cancer       Date:  2008-10-28       Impact factor: 7.640
  2 in total

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