Literature DB >> 10730622

The prevalence of cardiomyopathy in the Irish wolfhound: a clinical study of 500 dogs.

A C Vollmar1.   

Abstract

The prevalence of cardiomyopathy in Irish wolfhounds was evaluated by retrospective review of the results of cardiovascular examinations carried out in 500 dogs presented for veterinary services at the author's practice. Abnormalities were found in 209 (41.8%) of the dogs examined. Dilated cardiomyopathy (DCM) was diagnosed in 121 (24.2%) of the dogs and was accompanied by atrial fibrillation in 106 dogs. Seventeen dogs were suffering from advanced congestive heart failure (CHF), and 55 dogs were suffering from mild to moderate CHF as a result of DCM. Congestive heart failure was most commonly characterized by mild to severe pleural effusion due to right-sided heart failure in addition to pulmonary edema. Rhythm disturbances without evidence of DCM were detected in 48 dogs. Forty dogs had echocardiographic abnormalities without signs of DCM. Soft to moderate mitral regurgitations were diagnosed in 13 (2.6%) of these 40 dogs examined. In 39 dogs that died as a result of DCM, the median survival time from the time of diagnosis was 5.1 months, and in 59 dogs with DCM that are still alive, the median survival time is 15.7 months.

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Year:  2000        PMID: 10730622     DOI: 10.5326/15473317-36-2-125

Source DB:  PubMed          Journal:  J Am Anim Hosp Assoc        ISSN: 0587-2871            Impact factor:   1.023


  16 in total

Review 1.  Genetic Basis of Dilated Cardiomyopathy in Dogs and Its Potential as a Bidirectional Model.

Authors:  Karen R Gaar-Humphreys; Talitha C F Spanjersberg; Giorgia Santarelli; Guy C M Grinwis; Viktor Szatmári; Bernard A J Roelen; Aryan Vink; J Peter van Tintelen; Folkert W Asselbergs; Hille Fieten; Magdalena Harakalova; Frank G van Steenbeek
Journal:  Animals (Basel)       Date:  2022-06-29       Impact factor: 3.231

2.  Finding cardiovascular disease genes in the dog.

Authors:  Heidi G Parker; Kathryn M Meurs; Elaine A Ostrander
Journal:  J Vet Cardiol       Date:  2006-10-10       Impact factor: 1.701

3.  Multiple Loci are associated with dilated cardiomyopathy in Irish wolfhounds.

Authors:  Ute Philipp; Andrea Vollmar; Jens Häggström; Anne Thomas; Ottmar Distl
Journal:  PLoS One       Date:  2012-06-25       Impact factor: 3.240

4.  Multiple Genetic Associations with Irish Wolfhound Dilated Cardiomyopathy.

Authors:  Siobhan Simpson; Mark D Dunning; Serena Brownlie; Janika Patel; Megan Godden; Malcolm Cobb; Nigel P Mongan; Catrin S Rutland
Journal:  Biomed Res Int       Date:  2016-12-13       Impact factor: 3.411

5.  Retrospective Evaluation of the Effect of Heart Rate on Survival in Dogs with Atrial Fibrillation.

Authors:  B Pedro; J Dukes-McEwan; M A Oyama; M S Kraus; A R Gelzer
Journal:  J Vet Intern Med       Date:  2017-12-04       Impact factor: 3.333

6.  2-Deoxyadenosine triphosphate restores the contractile function of cardiac myofibril from adult dogs with naturally occurring dilated cardiomyopathy.

Authors:  Yuanhua Cheng; Kaley A Hogarth; M Lynne O'Sullivan; Michael Regnier; W Glen Pyle
Journal:  Am J Physiol Heart Circ Physiol       Date:  2015-10-23       Impact factor: 4.733

7.  Detection and comparison of microRNA expression in the serum of Doberman Pinschers with dilated cardiomyopathy and healthy controls.

Authors:  Carola Steudemann; Stefan Bauersachs; Karin Weber; Gerhard Wess
Journal:  BMC Vet Res       Date:  2013-01-17       Impact factor: 2.741

Review 8.  Genetics of Human and Canine Dilated Cardiomyopathy.

Authors:  Siobhan Simpson; Jennifer Edwards; Thomas F N Ferguson-Mignan; Malcolm Cobb; Nigel P Mongan; Catrin S Rutland
Journal:  Int J Genomics       Date:  2015-07-22       Impact factor: 2.326

9.  Pharmacokinetic study and evaluation of the safety of taurolidine for dogs with osteosarcoma.

Authors:  Kevin Marley; Stuart C Helfand; Jennifer Simpson; John E Mata; William G Tracewell; Lisa Brownlee; Shay Bracha; Bernard Séguin
Journal:  J Exp Clin Cancer Res       Date:  2013-10-11

10.  Long-term Outcome of Irish Wolfhound Dogs with Preclinical Cardiomyopathy, Atrial Fibrillation, or Both Treated with Pimobendan, Benazepril Hydrochloride, or Methyldigoxin Monotherapy.

Authors:  A C Vollmar; P R Fox
Journal:  J Vet Intern Med       Date:  2016-03-03       Impact factor: 3.333

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