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Literature DB >> 10729929

Neurotransmitter dysfunction in patients with borderline personality disorder.

I G Gurvits¹, H W Koenigsberg, L J Siever.

Abstract

Neurotransmitter system dysfunction may contribute to the borderline personality disorder traits of impulsive aggression and affective instability. This article reviews evidence from neurochemical assays, receptor-density studies, neuroendocrine-challenge paradigms, functional neuroimaging studies, and candidate-gene research, which converge to identify particular neurotransmitter systems that seem to be dysregulated in patients with borderline personality disorder.

Entities: Disease Species

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Year: 2000 PMID： 10729929 DOI： 10.1016/s0193-953x(05)70141-6

Source DB: PubMed Journal: Psychiatr Clin North Am ISSN： 0193-953X

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Cited

13 in total

1. Tryptophan-hydroxylase 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy controls.

Authors: M Mercedes Perez-Rodriguez; Shauna Weinstein; Antonia S New; Laura Bevilacqua; Qiaoping Yuan; Zhifeng Zhou; Colin Hodgkinson; Marianne Goodman; Harold W Koenigsberg; David Goldman; Larry J Siever
Journal: J Psychiatr Res Date: 2010-05-06 Impact factor: 4.791

Review 2. Borderline personality disorder.

Authors: Joel Paris
Journal: CMAJ Date: 2005-06-07 Impact factor: 8.262

10. Disentangling emotion processes in borderline personality disorder: physiological and self-reported assessment of biological vulnerability, baseline intensity, and reactivity to emotionally evocative stimuli.

Authors: Janice R Kuo; Marsha M Linehan
Journal: J Abnorm Psychol Date: 2009-08

Neurotransmitter dysfunction in patients with borderline personality disorder.

1. Tryptophan-hydroxylase 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy controls.

Review 2. Borderline personality disorder.

Review 3. Pharmacotherapy for borderline personality disorder--current evidence and recent trends.

Review 4. Attachment and its vicissitudes in borderline personality disorder.

Review 5. NMDA neurotransmission as a critical mediator of borderline personality disorder.

Review 6. Emotion-based dispositions to rash action: positive and negative urgency.

Review 7. The interpersonal dimension of borderline personality disorder: toward a neuropeptide model.

8. Adult attachment, personality traits, and borderline personality disorder features in young adults.

Review 9. A biosocial developmental model of borderline personality: Elaborating and extending Linehan's theory.

10. Disentangling emotion processes in borderline personality disorder: physiological and self-reported assessment of biological vulnerability, baseline intensity, and reactivity to emotionally evocative stimuli.