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Literature DB >> 10729166

Ultrastructural organization of recombinant Marburg virus nucleoprotein: comparison with Marburg virus inclusions.

L Kolesnikova¹, E Mühlberger, E Ryabchikova, S Becker.

Abstract

HeLa cells expressing the recombinant Marburg virus (MBGV) nucleoprotein (NP) have been studied by immunoelectron microscopy. It was found that MBGV NPs assembled into large aggregates which were in close association with membranes of the rough endoplasmic reticulum. Further analysis of these aggregates revealed that NPs formed tubule-like structures which were arranged in a hexagonal pattern. A similar pattern of preformed nucleocapsids was detected in intracellular inclusions induced by MBGV infection. Our data indicated that MBGV NP is able to form nucleocapsid-like structures in the absence of the authentic viral genome and other nucleocapsid-associated proteins.

Entities: Disease Gene

Mesh：

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Year: 2000 PMID： 10729166 PMCID： PMC111900 DOI： 10.1128/jvi.74.8.3899-3904.2000

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

21 in total

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Authors: S Becker; C Rinne; U Hofsäss; H D Klenk; E Mühlberger
Journal: Virology Date: 1998-09-30 Impact factor: 3.616

2. Three of the four nucleocapsid proteins of Marburg virus, NP, VP35, and L, are sufficient to mediate replication and transcription of Marburg virus-specific monocistronic minigenomes.

Authors: E Mühlberger; B Lötfering; H D Klenk; S Becker
Journal: J Virol Date: 1998-11 Impact factor: 5.103

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Authors: T W Geisbert; P B Jahrling
Journal: Virus Res Date: 1995-12 Impact factor: 3.303

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Authors: C J Buchholz; D Spehner; R Drillien; W J Neubert; H E Homann
Journal: J Virol Date: 1993-10 Impact factor: 5.103

5. The nucleoprotein of Marburg virus is phosphorylated.

Authors: S Becker; S Huppertz; H D Klenk; H Feldmann
Journal: J Gen Virol Date: 1994-04 Impact factor: 3.891

6. Marburg hemorrhagic fever: report of a case studied by immunohistochemistry and electron microscopy.

Authors: T W Geisbert; N K Jaax
Journal: Ultrastruct Pathol Date: 1998 Jan-Feb Impact factor: 1.094

7. Respiratory Marburg virus infection in guinea pigs.

Authors: E Ryabchikova; L Strelets; L Kolesnikova; O Pyankov; A Sergeev
Journal: Arch Virol Date: 1996 Impact factor: 2.574

8. Intracellular transport and processing of the Marburg virus surface protein in vertebrate and insect cells.

Authors: S Becker; H D Klenk; E Mühlberger
Journal: Virology Date: 1996-11-01 Impact factor: 3.616

9. Non-replicating vaccinia vector efficiently expresses bacteriophage T7 RNA polymerase.

Authors: G Sutter; M Ohlmann; V Erfle
Journal: FEBS Lett Date: 1995-08-28 Impact factor: 4.124

10. The complete nucleotide sequence of the Popp (1967) strain of Marburg virus: a comparison with the Musoke (1980) strain.

Authors: A A Bukreyev; V E Volchkov; V M Blinov; S A Dryga; S V Netesov
Journal: Arch Virol Date: 1995 Impact factor: 2.574

48 in total

1. Sorting of Marburg virus surface protein and virus release take place at opposite surfaces of infected polarized epithelial cells.

Authors: C Sänger; E Mühlberger; E Ryabchikova; L Kolesnikova; H D Klenk; S Becker
Journal: J Virol Date: 2001-02 Impact factor: 5.103

2. VP40, the matrix protein of Marburg virus, is associated with membranes of the late endosomal compartment.

Authors: Larissa Kolesnikova; Harald Bugany; Hans-Dieter Klenk; Stephan Becker
Journal: J Virol Date: 2002-02 Impact factor: 5.103

3. The matrix protein of Marburg virus is transported to the plasma membrane along cellular membranes: exploiting the retrograde late endosomal pathway.

Authors: Larissa Kolesnikova; Sandra Bamberg; Beate Berghöfer; Stephan Becker
Journal: J Virol Date: 2004-03 Impact factor: 5.103

4. Recombinant Marburg virus expressing EGFP allows rapid screening of virus growth and real-time visualization of virus spread.

Authors: Kristina Maria Schmidt; Michael Schümann; Judith Olejnik; Verena Krähling; Elke Mühlberger
Journal: J Infect Dis Date: 2011-11 Impact factor: 5.226

5. Tsg101 is recruited by a late domain of the nucleocapsid protein to support budding of Marburg virus-like particles.

Authors: Olga Dolnik; Larissa Kolesnikova; Lea Stevermann; Stephan Becker
Journal: J Virol Date: 2010-05-26 Impact factor: 5.103

6. Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations.

Authors: Jens H Kuhn; Stephan Becker; Hideki Ebihara; Thomas W Geisbert; Karl M Johnson; Yoshihiro Kawaoka; W Ian Lipkin; Ana I Negredo; Sergey V Netesov; Stuart T Nichol; Gustavo Palacios; Clarence J Peters; Antonio Tenorio; Viktor E Volchkov; Peter B Jahrling
Journal: Arch Virol Date: 2010-10-30 Impact factor: 2.574