Literature DB >> 10728987

TGFbeta signaling pathways and human diseases.

R W Padgett1.   

Abstract

Recent progress in deciphering the TGFbeta pathway has uncovered a new signaling molecule, the Smads, and with this finding now gives us insights into how TGFbeta-like signals are transmitted from outside the cell to the nucleus. As we learn more about how TGFbeta regulates normal development, we also are gaining insights into diseases that are caused by mis-regulation or mutation of various components of the signaling pathways.

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Year:  1999        PMID: 10728987     DOI: 10.1023/a:1006325408261

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN: 0167-7659            Impact factor:   9.264


  4 in total

1.  Differential regulation of survivin expression and apoptosis by vitamin D3 compounds in two isogenic MCF-7 breast cancer cell sublines.

Authors:  Fengzhi Li; Xiang Ling; Huayi Huang; Lisa Brattain; Pasha Apontes; Jianguo Wu; Lise Binderup; Michael G Brattain
Journal:  Oncogene       Date:  2005-02-17       Impact factor: 9.867

Review 2.  TGF-beta3 and cancer: a review.

Authors:  H G Laverty; L M Wakefield; N L Occleston; S O'Kane; M W J Ferguson
Journal:  Cytokine Growth Factor Rev       Date:  2009-08-04       Impact factor: 7.638

Review 3.  The Smads.

Authors:  L Attisano; S T Lee-Hoeflich
Journal:  Genome Biol       Date:  2001-08-02       Impact factor: 13.583

4.  C. elegans SMA-10 regulates BMP receptor trafficking.

Authors:  Ryan J Gleason; Mehul Vora; Ying Li; Nanci S Kane; Kelvin Liao; Richard W Padgett
Journal:  PLoS One       Date:  2017-07-13       Impact factor: 3.240

  4 in total

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