Literature DB >> 10727811

Antipyretic, antinociceptive and anti-inflammatory activity of Premna herbacea roots.

N Narayanan1, P Thirugnanasambantham, S Viswanathan, M Kannappa Reddy, V Vijayasekaran, E Sukumar.   

Abstract

The alcoholic extract of the roots of Premna herbacea was investigated for its antipyretic, antinociceptive and anti-inflammatory potential in animal models. The extract, when administered orally to mice has been found to be safe up to a dose of 8.0 g/kg. A significant antipyretic effect has been observed in rabbits while mild antinociceptive effects were evidenced in mice when tested by chemical as well as thermal methods. The extract did not exhibit any anti-inflammatory activity in acute but significantly reduced the chronic inflammation.

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Year:  2000        PMID： 10727811     DOI： 10.1016/s0367-326x(99)00132-x

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  6 in total

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Authors:  Subash C Gupta; Ramaswamy Kannappan; Jihye Kim; Ghazi M Rahman; Sajin K Francis; Reshma Raveendran; Mangalam S Nair; Joydip Das; Bharat B Aggarwal
Journal:  Mol Pharmacol       Date:  2011-07-27       Impact factor: 4.436

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Authors:  Shruti Mishra; Sumit S Verma; Vipin Rai; Nikee Awasthee; Srinivas Chava; Kam Man Hui; Alan Prem Kumar; Kishore B Challagundla; Gautam Sethi; Subash C Gupta
Journal:  Cell Mol Life Sci       Date:  2019-03-16       Impact factor: 9.261

3.  Antinociceptive and Antioxidant Activities of Phytol In Vivo and In Vitro Models.

Authors:  Camila Carolina de Menezes Patrício Santos; Mirian Stiebbe Salvadori; Vanine Gomes Mota; Luciana Muratori Costa; Antonia Amanda Cardoso de Almeida; Guilherme Antônio Lopes de Oliveira; Jéssica Pereira Costa; Damião Pergentino de Sousa; Rivelilson Mendes de Freitas; Reinaldo Nóbrega de Almeida
Journal:  Neurosci J       Date:  2013-06-11

Review 4.  Ethnomedicinal uses, phytochemistry and pharmacological aspects of the genus Premna: a review.

Authors:  Roza Dianita; Ibrahim Jantan
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

5.  Isolation, identification and bioactivities of abietane diterpenoids from Premna szemaoensis.

Authors:  De-Bing Pu; Ting Wang; Xing-Jie Zhang; Jun-Bo Gao; Rui-Han Zhang; Xiao-Nian Li; Yong-Mei Wang; Xiao-Li Li; He-Yao Wang; Wei-Lie Xiao
Journal:  RSC Adv       Date:  2018-02-09       Impact factor: 3.361

Review 6.  Lamiaceae in Mexican Species, a Great but Scarcely Explored Source of Secondary Metabolites with Potential Pharmacological Effects in Pain Relief.

Authors:  Alberto Hernandez-Leon; Gabriel Fernando Moreno-Pérez; Martha Martínez-Gordillo; Eva Aguirre-Hernández; María Guadalupe Valle-Dorado; María Irene Díaz-Reval; María Eva González-Trujano; Francisco Pellicer
Journal:  Molecules       Date:  2021-12-16       Impact factor: 4.411
  6 in total

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