Literature DB >> 10727728

Localization of mRNAs for phospholipase D (PLD) type 1 and 2 in the brain of developing and mature rat.

S Saito1, H Sakagami, H Kondo.   

Abstract

Phospholipase D (PLD) is known as one of the key enzymes in the lipid metabolism which produces several second messengers. We demonstrated the localization of the gene expression for PLD1 and PLD2 using in situ hybridization histochemistry in the brain of developing and mature rats. Whereas PLD1 mRNA expression was detected mainly in presumptive oligodendrocytes, PLD2 mRNA expression was detected mainly in presumptive astrocytes. In addition, the gene expression for PLDs were expressed in neuroepithelial cells of the ventricular/ependymal zones and the gene for PLD2 was expressed transiently in early postnatal gray matters, presumptive neurons.

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Year:  2000        PMID: 10727728     DOI: 10.1016/s0165-3806(99)00189-3

Source DB:  PubMed          Journal:  Brain Res Dev Brain Res        ISSN: 0165-3806


  7 in total

1.  The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.

Authors:  Ville A B Palomäki; Jarmo T Laitinen
Journal:  Br J Pharmacol       Date:  2006-03       Impact factor: 8.739

2.  Down-regulation of phospholipase D2 mRNA in neonatal rat brainstem and cerebellum after hypoxia-ischemia.

Authors:  Jeng-Hsiung F Peng; Yangzheng Feng; Philip G Rhodes
Journal:  Neurochem Res       Date:  2006-10-06       Impact factor: 3.996

3.  Regulation of neuroblast mitosis is determined by PACAP receptor isoform expression.

Authors:  A Nicot; E DiCicco-Bloom
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-10       Impact factor: 11.205

Review 4.  Phosphatidic acid-producing enzymes regulating the synaptic vesicle cycle: Role for PLD?

Authors:  Casey N Barber; Richard L Huganir; Daniel M Raben
Journal:  Adv Biol Regul       Date:  2017-09-28

5.  Phospholipase D family member 4, a transmembrane glycoprotein with no phospholipase D activity, expression in spleen and early postnatal microglia.

Authors:  Fumio Yoshikawa; Yoshiko Banno; Yoshinori Otani; Yoshihide Yamaguchi; Yuko Nagakura-Takagi; Noriyuki Morita; Yumi Sato; Chihiro Saruta; Hirozumi Nishibe; Tetsushi Sadakata; Yo Shinoda; Kanehiro Hayashi; Yuriko Mishima; Hiroko Baba; Teiichi Furuichi
Journal:  PLoS One       Date:  2010-11-11       Impact factor: 3.240

6.  Generation of choline for acetylcholine synthesis by phospholipase D isoforms.

Authors:  D Zhao; M A Frohman; J K Blusztajn
Journal:  BMC Neurosci       Date:  2001-10-19       Impact factor: 3.288

Review 7.  Mammalian phospholipase D: Function, and therapeutics.

Authors:  M I McDermott; Y Wang; M J O Wakelam; V A Bankaitis
Journal:  Prog Lipid Res       Date:  2019-12-09       Impact factor: 16.195

  7 in total

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