Literature DB >> 10727199

A paradoxical rise of neonatal seizures after treatment with vitamin B6.

A Hammen1, B Wagner, M Berkhoff, F Donati.   

Abstract

We report the case of a newborn with intractable epileptic seizures developing a paradoxical rise of seizure frequency and electroencephalogram alterations after administration of vitamin B6. We have been unable to determine the aetiology of this disorder. In a newborn presenting with drug-resistant epileptic seizures, the first therapeutic option remains the application of intravenous pyridoxine, but the physician should be aware of the risk of an increase in seizure frequency.

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Year:  1998        PMID： 10727199     DOI： 10.1016/s1090-3798(98)80007-x

Source DB:  PubMed          Journal:  Eur J Paediatr Neurol        ISSN： 1090-3798            Impact factor:   3.140


  6 in total

1.  Current treatment and management of pyridoxine-dependent epilepsy.

Authors:  Clara D M van Karnebeek; Sravan Jaggumantri
Journal:  Curr Treat Options Neurol       Date:  2015-02       Impact factor: 3.598

Review 2.  B6-responsive disorders: a model of vitamin dependency.

Authors:  Peter T Clayton
Journal:  J Inherit Metab Dis       Date:  2006 Apr-Jun       Impact factor: 4.982

3.  Pyridoxal phosphate is better than pyridoxine for controlling idiopathic intractable epilepsy.

Authors:  H-S Wang; M-F Kuo; M-L Chou; P-C Hung; K-L Lin; M-Y Hsieh; M-Y Chang
Journal:  Arch Dis Child       Date:  2005-05       Impact factor: 3.791

4.  Measurement of plasma B6 vitamer profiles in children with inborn errors of vitamin B6 metabolism using an LC-MS/MS method.

Authors:  Emma J Footitt; Peter T Clayton; Kevin Mills; Simon J Heales; Viruna Neergheen; Marcus Oppenheim; Philippa B Mills
Journal:  J Inherit Metab Dis       Date:  2012-05-11       Impact factor: 4.982

5.  Pyridoxamine Supplementation Effectively Reverses the Abnormal Phenotypes of Zebrafish Larvae With PNPO Deficiency.

Authors:  Po-Yuan Chen; Hung-Chi Tu; Verne Schirch; Martin K Safo; Tzu-Fun Fu
Journal:  Front Pharmacol       Date:  2019-09-20       Impact factor: 5.810

6.  Epilepsy due to PNPO mutations: genotype, environment and treatment affect presentation and outcome.

Authors:  Philippa B Mills; Stephane S M Camuzeaux; Emma J Footitt; Kevin A Mills; Paul Gissen; Laura Fisher; Krishna B Das; Sophia M Varadkar; Sameer Zuberi; Robert McWilliam; Tommy Stödberg; Barbara Plecko; Matthias R Baumgartner; Oliver Maier; Sophie Calvert; Kate Riney; Nicole I Wolf; John H Livingston; Pronab Bala; Chantal F Morel; François Feillet; Francesco Raimondi; Ennio Del Giudice; W Kling Chong; Matthew Pitt; Peter T Clayton
Journal:  Brain       Date:  2014-03-18       Impact factor: 13.501
  6 in total

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