Literature DB >> 10726926

Decatromicins A and B, new antibiotics produced by Actinomadura sp. MK73-NF4. II. Structure determination.

I Momose1, S Hirosawa, H Nakamura, H Naganawa, H Iinuma, D Ikeda, T Takeuchi.   

Abstract

The structures of decatromicins A and B that strongly inhibit the growth of MRSA were elucidated by the analysis of various NMR experiments. The planar structure was determined by 1H, 13C, COSY, HMQC and HMBC NMR spectra. The relative configuration of aglycone was elucidated by NOESY experiments and the absolute structure was determined by application of the modified Mosher's method. The absolute structure of glycosyl moiety was determined by X-ray analysis of the O-(p-bromobenzoyl) derivative.

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Year:  1999        PMID： 10726926     DOI： 10.7164/antibiotics.52.787

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  6 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

Review 2.  Astonishing diversity of natural surfactants: 2. Polyether glycosidic ionophores and macrocyclic glycosides.

Authors:  Valery M Dembitsky
Journal:  Lipids       Date:  2005-03       Impact factor: 1.880

3.  Spirotetronate antibiotics with anti-Clostridium activity from Actinomadura sp. 2EPS.

Authors:  Jirayut Euanorasetr; Bungonsiri Intra; Phayungsak Mongkol; Surang Chankhamhaengdecha; Patoomratana Tuchinda; Mihoko Mori; Kazuro Shiomi; Takuya Nihira; Watanalai Panbangred
Journal:  World J Microbiol Biotechnol       Date:  2014-12-28       Impact factor: 3.312

4.  Structure and activity of lobophorins from a turrid mollusk-associated Streptomyces sp.

Authors:  Zhenjian Lin; Michael Koch; Christopher D Pond; Gaiselle Mabeza; Romell A Seronay; Gisela P Concepcion; Louis R Barrows; Baldomero M Olivera; Eric W Schmidt
Journal:  J Antibiot (Tokyo)       Date:  2013-11-13       Impact factor: 2.649

Review 5.  Spirotetronate polyketides as leads in drug discovery.

Authors:  Michelle H Lacoske; Emmanuel A Theodorakis
Journal:  J Nat Prod       Date:  2014-12-01       Impact factor: 4.050

6.  New spirotetronate antibiotics, lobophorins H and I, from a South China Sea-derived Streptomyces sp. 12A35.

Authors:  Hua-Qi Pan; Song-Ya Zhang; Nan Wang; Zhan-Lin Li; Hui-Ming Hua; Jiang-Chun Hu; Shu-Jin Wang
Journal:  Mar Drugs       Date:  2013-10-15       Impact factor: 5.118
  6 in total

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