Literature DB >> 10724287

Becaplermin gel (PDGF-BB) as topical wound therapy. Plastic Surgery Educational Foundation DATA Committee.

D Ladin1.   

Abstract

Becaplermin gel is the first topical growth factor to demonstrate therapeutic efficacy in the healing of diabetic wounds. For diabetic patients who have poorly healing ulcers despite good perfusion and a reasonable trial of wound care, this product may be of considerable benefit. It should be tried for a 2-week time period and the results objectively assessed before continuation of therapy.

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Year:  2000        PMID: 10724287     DOI: 10.1097/00006534-200003000-00065

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  6 in total

Review 1.  Healing the diabetic wound and keeping it healed: modalities for the early 21st century.

Authors:  Matthew J Claxton; David G Armstrong; Andrew J M Boulton
Journal:  Curr Diab Rep       Date:  2002-12       Impact factor: 4.810

Review 2.  Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 2: role of growth factors in normal and pathological wound healing: therapeutic potential and methods of delivery.

Authors:  Tatiana N Demidova-Rice; Michael R Hamblin; Ira M Herman
Journal:  Adv Skin Wound Care       Date:  2012-08       Impact factor: 2.347

Review 3.  Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases.

Authors:  Yihai Cao
Journal:  Nat Rev Drug Discov       Date:  2010-02       Impact factor: 84.694

Review 4.  The role of vascular endothelial growth factor in wound healing.

Authors:  Philip Bao; Arber Kodra; Marjana Tomic-Canic; Michael S Golinko; H Paul Ehrlich; Harold Brem
Journal:  J Surg Res       Date:  2008-05-12       Impact factor: 2.192

Review 5.  Topical gel-based biomaterials for the treatment of diabetic foot ulcers.

Authors:  James R Bardill; Melissa R Laughter; Michael Stager; Kenneth W Liechty; Melissa D Krebs; Carlos Zgheib
Journal:  Acta Biomater       Date:  2021-10-30       Impact factor: 8.947

6.  Functional Mining of the Crotalus Spp. Venom Protease Repertoire Reveals Potential for Chronic Wound Therapeutics.

Authors:  David Meléndez-Martínez; Luis Fernando Plenge-Tellechea; Ana Gatica-Colima; Martha Sandra Cruz-Pérez; José Manuel Aguilar-Yáñez; Cuauhtémoc Licona-Cassani
Journal:  Molecules       Date:  2020-07-28       Impact factor: 4.411

  6 in total

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