Literature DB >> 10724007

Haematocin, a new antifungal diketopiperazine produced by Nectria haematococca Berk. et Br. (880701a-1) causing nectria blight disease on ornamental plants.

Y Suzuki1, H Takahashi, Y Esumi, T Arie, T Morita, H Koshino, J Uzawa, M Uramoto, I Yamaguchi.   

Abstract

A new antifungal diketopiperazine named haematocin was isolated from the culture broth of Nectria haematococca Berk. et Br. (880701a-1) causing blight disease on ornamental plants, Phalaenopsis spp. and Doritanopsis spp. Its structure was established by spectroscopic methods. Haematocin inhibited the germ-tube elongation and spore-germination of Pyricularia oryzae at the ED50 values of 30 microg/ml and 160 microg/ml, respectively.

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Year:  2000        PMID: 10724007     DOI: 10.7164/antibiotics.53.45

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  7 in total

1.  Synthesis and biological evaluation of epidithio-, epitetrathio-, and bis-(methylthio)diketopiperazines: synthetic methodology, enantioselective total synthesis of epicoccin G, 8,8'-epi-ent-rostratin B, gliotoxin, gliotoxin G, emethallicin E, and haematocin and discovery of new antiviral and antimalarial agents.

Authors:  K C Nicolaou; Min Lu; Sotirios Totokotsopoulos; Philipp Heretsch; Denis Giguère; Ya-Ping Sun; David Sarlah; Thu H Nguyen; Ian C Wolf; Donald F Smee; Craig W Day; Selina Bopp; Elizabeth A Winzeler
Journal:  J Am Chem Soc       Date:  2012-10-04       Impact factor: 15.419

2.  Graphiumins, new thiodiketopiperazines from the marine-derived fungus Graphium sp. OPMF00224.

Authors:  Takashi Fukuda; Minori Shinkai; Eri Sasaki; Kenichiro Nagai; Yuko Kurihara; Akihiko Kanamoto; Hiroshi Tomoda
Journal:  J Antibiot (Tokyo)       Date:  2015-04-22       Impact factor: 2.649

3.  Streptomyces coeruleorubidus as a potential biocontrol agent for Newcastle disease virus.

Authors:  Rewan Abdelaziz; Yasmine H Tartor; Ahmed B Barakat; Gamal El-Didamony; Hanaa A El-Samadony; Shimaa A Amer; Marwa M Gado
Journal:  BMC Vet Res       Date:  2022-06-24       Impact factor: 2.792

4.  Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis.

Authors:  Chun-Jun Guo; Hsu-Hua Yeh; Yi-Ming Chiang; James F Sanchez; Shu-Ling Chang; Kenneth S Bruno; Clay C C Wang
Journal:  J Am Chem Soc       Date:  2013-05-01       Impact factor: 15.419

5.  Preparative separation of sulfur-containing diketopiperazines from marine fungus Cladosporium sp. using high-speed counter-current chromatography in stepwise elution mode.

Authors:  Binbin Gu; Yanying Zhang; Lijian Ding; Shan He; Bin Wu; Junde Dong; Peng Zhu; Juanjuan Chen; Jinrong Zhang; Xiaojun Yan
Journal:  Mar Drugs       Date:  2015-01-09       Impact factor: 5.118

6.  Efficient Preparation of Streptochlorin from Marine Streptomyces sp. SYYLWHS-1-4 by Combination of Response Surface Methodology and High-Speed Counter-Current Chromatography.

Authors:  Lin Li; Shan He; Lijian Ding; Ye Yuan; Peng Zhu; Slava Epstein; Jianzhong Fan; Xiaokai Wu; Xiaojun Yan
Journal:  Molecules       Date:  2016-05-27       Impact factor: 4.411

Review 7.  Structural Diversity and Biological Activities of the Cyclodipeptides from Fungi.

Authors:  Xiaohan Wang; Yuying Li; Xuping Zhang; Daowan Lai; Ligang Zhou
Journal:  Molecules       Date:  2017-11-23       Impact factor: 4.411

  7 in total

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