Literature DB >> 10722647

Molecular and immunological analyses of the Borrelia turicatae Bdr protein family.

J A Carlyon1, D M Roberts, M Theisen, C Sadler, R T Marconi.   

Abstract

Here, we describe the molecular and immunological characterization of the bdr gene family of Borrelia turicatae, a relapsing-fever spirochete. Nine bdr alleles belonging to two different subfamilies were sequenced and localized to linear plasmids. Anti-Bdr antiserum was generated and used to analyze Bdr expression in pre- and postinfection isogenic populations. The analyses presented here provide a detailed characterization of the Bdr proteins in a relapsing-fever spirochete species, enhancing our understanding of these proteins at the genus-wide level.

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Year:  2000        PMID: 10722647      PMCID: PMC97431          DOI: 10.1128/IAI.68.4.2369-2373.2000

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  26 in total

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2.  Mutation and recombination in the upstream homology box-flanked ospE-related genes of the Lyme disease spirochetes result in the development of new antigenic variants during infection.

Authors:  S Y Sung; J V McDowell; J A Carlyon; R T Marconi
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3.  High resolution two-dimensional electrophoresis of proteins.

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Authors:  L Shi; M Potts; P J Kennelly
Journal:  FEMS Microbiol Rev       Date:  1998-10       Impact factor: 16.408

Review 5.  Biology of Borrelia species.

Authors:  A G Barbour; S F Hayes
Journal:  Microbiol Rev       Date:  1986-12

6.  Identification, characterization, and expression of three new members of the Borrelia burgdorferi Mlp (2.9) lipoprotein gene family.

Authors:  X Yang; T G Popova; K E Hagman; S K Wikel; G B Schoeler; M J Caimano; J D Radolf; M V Norgard
Journal:  Infect Immun       Date:  1999-11       Impact factor: 3.441

7.  Transcriptional start and MetR binding sites on the Escherichia coli metH gene.

Authors:  R Marconi; J Wigboldus; H Weissbach; N Brot
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8.  An OspB mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo.

Authors:  A Sadziene; A G Barbour; P A Rosa; D D Thomas
Journal:  Infect Immun       Date:  1993-09       Impact factor: 3.441

9.  Low-passage-associated proteins of Borrelia burgdorferi B31: characterization and molecular cloning of OspD, a surface-exposed, plasmid-encoded lipoprotein.

Authors:  S J Norris; C J Carter; J K Howell; A G Barbour
Journal:  Infect Immun       Date:  1992-11       Impact factor: 3.441

Review 10.  The bdr gene families of the Lyme disease and relapsing fever spirochetes: potential influence on biology, pathogenesis, and evolution.

Authors:  D M Roberts; J A Carlyon; M Theisen; R T Marconi
Journal:  Emerg Infect Dis       Date:  2000 Mar-Apr       Impact factor: 6.883

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  9 in total

1.  Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions.

Authors:  Elizabeth A Rogers; Darya Terekhova; Hong-Ming Zhang; Kelley M Hovis; Ira Schwartz; Richard T Marconi
Journal:  Mol Microbiol       Date:  2009-01-23       Impact factor: 3.501

2.  Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relapsing fever in Florida.

Authors:  Tom G Schwan; Sandra J Raffel; Merry E Schrumpf; Paul F Policastro; Julie A Rawlings; Robert S Lane; Edward B Breitschwerdt; Stephen F Porcella
Journal:  J Clin Microbiol       Date:  2005-08       Impact factor: 5.948

3.  Environmental regulation and differential production of members of the Bdr protein family of Borrelia burgdorferi.

Authors:  David M Roberts; Melissa Caimano; John McDowell; Michael Theisen; Arne Holm; Edward Orff; David Nelson; Stephen Wikel; Justin Radolf; Richard T Marconi
Journal:  Infect Immun       Date:  2002-12       Impact factor: 3.441

4.  Analysis of the cellular localization of Bdr paralogs in Borrelia burgdorferi, a causative agent of lyme disease: evidence for functional diversity.

Authors:  D M Roberts; M Theisen; R T Marconi
Journal:  J Bacteriol       Date:  2000-08       Impact factor: 3.490

5.  bdrF2 of Lyme disease spirochetes is coexpressed with a series of cytoplasmic proteins and is produced specifically during early infection.

Authors:  Hongming Zhang; Abayami Raji; Michael Theisen; Paul R Hansen; Richard T Marconi
Journal:  J Bacteriol       Date:  2005-01       Impact factor: 3.490

6.  Analysis of mechanisms associated with loss of infectivity of clonal populations of Borrelia burgdorferi B31MI.

Authors:  J V McDowell; S Y Sung; M Labandeira-Rey; J T Skare; R T Marconi
Journal:  Infect Immun       Date:  2001-06       Impact factor: 3.441

7.  Characterization of P40, a cytadhesin of Mycoplasma agalactiae.

Authors:  Bénédicte Fleury; Dominique Bergonier; Xavier Berthelot; Ernst Peterhans; Joachim Frey; Edy M Vilei
Journal:  Infect Immun       Date:  2002-10       Impact factor: 3.441

8.  Identification and characterization of a linear-plasmid-encoded factor H-binding protein (FhbA) of the relapsing fever spirochete Borrelia hermsii.

Authors:  Kelley M Hovis; John V McDowell; LaToya Griffin; Richard T Marconi
Journal:  J Bacteriol       Date:  2004-05       Impact factor: 3.490

9.  Intra- and interbacterial genetic exchange of Lyme disease spirochete erp genes generates sequence identity amidst diversity.

Authors:  Brian Stevenson; Jennifer C Miller
Journal:  J Mol Evol       Date:  2003-09       Impact factor: 2.395

  9 in total

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