Literature DB >> 10721938

History of zinc as related to brain function.

H H Sandstead1, C J Frederickson, J G Penland.   

Abstract

Zinc (Zn) is essential for synthesis of coenzymes that mediate biogenic-amine synthesis and metabolism. Zn from vesicles in presynaptic terminals of certain glutaminergic neurons modulates postsynaptic N-methyl-D-aspartate (NMDA) receptors for glutamate. Large amounts of Zn released from vesicles by seizures or ischemia can kill postsynaptic neurons. Acute Zn deficiency impairs brain function of experimental animals and humans. Zn deficiency in experimental animals during early brain development causes malformations, whereas deficiency later in brain development causes microscopic abnormalities and impairs subsequent function. A limited number of studies suggest that similar phenomena can occur in humans.

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Year:  2000        PMID: 10721938     DOI: 10.1093/jn/130.2.496S

Source DB:  PubMed          Journal:  J Nutr        ISSN: 0022-3166            Impact factor:   4.798


  38 in total

1.  Selective, quantitative measurement of releasable synaptic zinc in human autopsy hippocampal brain tissue from Alzheimer's disease patients.

Authors:  Nicole L Bjorklund; V-M Sadagoparamanujam; Giulio Taglialatela
Journal:  J Neurosci Methods       Date:  2011-09-16       Impact factor: 2.390

2.  Cellular zinc and redox buffering capacity of metallothionein/thionein in health and disease.

Authors:  Wolfgang Maret; Artur Krezel
Journal:  Mol Med       Date:  2007 Jul-Aug       Impact factor: 6.354

3.  How does zinc supplementation benefit anorexia nervosa?

Authors:  C L Birmingham; S Gritzner
Journal:  Eat Weight Disord       Date:  2006-12       Impact factor: 4.652

4.  Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line.

Authors:  Emily Ho; Bruce N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-12       Impact factor: 11.205

Review 5.  Cognitive impairment, genomic instability and trace elements.

Authors:  A Meramat; N F Rajab; S Shahar; R Sharif
Journal:  J Nutr Health Aging       Date:  2015-01       Impact factor: 4.075

6.  Genetically Encoded, Photostable Indicators to Image Dynamic Zn2+ Secretion of Pancreatic Islets.

Authors:  Minghai Chen; Shen Zhang; Yuan Xing; Xinyu Li; Yi He; Yong Wang; José Oberholzer; Hui-Wang Ai
Journal:  Anal Chem       Date:  2019-09-10       Impact factor: 6.986

7.  Plasma trace elements and cognitive function in older men and women: the Rancho Bernardo study.

Authors:  P K Lam; D Kritz-Silverstein; E Barrett Connor; D Milne; F Nielsen; A Gamst; D Morton; D Wingard
Journal:  J Nutr Health Aging       Date:  2008-01       Impact factor: 4.075

Review 8.  Human zinc deficiency: discovery to initial translation.

Authors:  Harold H Sandstead
Journal:  Adv Nutr       Date:  2013-01-01       Impact factor: 8.701

Review 9.  Impaired calcium entry into cells is associated with pathological signs of zinc deficiency.

Authors:  Boyd L O'Dell; Jimmy D Browning
Journal:  Adv Nutr       Date:  2013-05-01       Impact factor: 8.701

10.  ZIP4 is a novel molecular marker for glioma.

Authors:  Yi Lin; Yong Chen; Yongzhi Wang; Jingxuan Yang; Vivian F Zhu; Yulun Liu; Xiaobo Cui; Leon Chen; Wei Yan; Tao Jiang; Georgene W Hergenroeder; Stephen A Fletcher; Jonathan M Levine; Dong H Kim; Nitin Tandon; Jay-Jiguang Zhu; Min Li
Journal:  Neuro Oncol       Date:  2013-04-17       Impact factor: 12.300

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