| Literature DB >> 10721419 |
Abstract
Thyroid transcription factor-1 (TTF-1) is a tissue specific transcription factor expressed in epithelial cells of the thyroid and lung, as well as in certain areas of the brain. Recent investigations have shown that TTF-1 is also commonly present in a wide variety of thyroid and lung tumors. Because of its restrictive expression, TTF-1 is a useful immunohistochemical marker in the diagnosis of tumors of thyroid or lung origin.Entities:
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Year: 2000 PMID: 10721419 DOI: 10.1097/00125480-200007020-00007
Source DB: PubMed Journal: Adv Anat Pathol ISSN: 1072-4109 Impact factor: 3.875