Literature DB >> 10721419

Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas.

N G Ordóñez1.   

Abstract

Thyroid transcription factor-1 (TTF-1) is a tissue specific transcription factor expressed in epithelial cells of the thyroid and lung, as well as in certain areas of the brain. Recent investigations have shown that TTF-1 is also commonly present in a wide variety of thyroid and lung tumors. Because of its restrictive expression, TTF-1 is a useful immunohistochemical marker in the diagnosis of tumors of thyroid or lung origin.

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Year:  2000        PMID: 10721419     DOI: 10.1097/00125480-200007020-00007

Source DB:  PubMed          Journal:  Adv Anat Pathol        ISSN: 1072-4109            Impact factor:   3.875


  40 in total

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