| Literature DB >> 10720787 |
C V Pantoja1, N T Martín, B C Norris, C M Contreras.
Abstract
The intravenous administration of a purified fraction (6 microg/kg) to anaesthesized dogs was followed by a significant biphasic diuretic and natriuretic response which reached a maximum at 180 min after injection. Chloride, but not potassium ions, followed the natriuretic profile. No changes were observed in arterial blood pressure or in the electrocardiogram. The purified garlic fraction also induced an inhibitory dose-dependent effect on kidney Na, K-ATPase.Entities:
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Year: 2000 PMID： 10720787 DOI： 10.1016/s0378-8741(99)00145-2
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360