Literature DB >> 10720784

Hypoglycaemic and other related actions of Tinospora cordifolia roots in alloxan-induced diabetic rats.

P Stanely1, M Prince, V P Menon.   

Abstract

Tinospora cordifolia is widely used in Indian Ayurvedic medicine for treating diabetes mellitus. Oral administration of an aqueous T. cordifolia root extract (TCREt) to alloxan diabetic rats caused a significant reduction in blood glucose and brain lipids. The extract caused an increase in body weight, total haemoglobin and hepatic hexokinase. The root extract also lowers hepatic glucose-6-phosphatase and serum acid phosphatase, alkaline phosphatase, and lactate dehydrogenase in diabetic rats. Thus TCREt has hypoglycaemic and hypolipidaemic effect.

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Year:  2000        PMID： 10720784     DOI： 10.1016/s0378-8741(99)00136-1

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  30 in total

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6.  The effects of aqueous extract of alfalfa on blood glucose and lipids in alloxan-induced diabetic rats.

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Journal:  Interv Med Appl Sci       Date:  2015-09-28

7.  Phytochemical Screening and Establishment of the Antidiabetic Potential of Aqueous Leaf Extract of the Endangered Plant Decalepis nervosa in Rats with Alloxan-induced Diabetes.

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8.  Polyphenolic-rich extracts of Andrographis paniculata mitigate hyperglycemia via attenuating β-cell dysfunction, pro-inflammatory cytokines and oxidative stress in alloxan-induced diabetic Wistar albino rat.

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9.  Hypoglycemic activity of Hemidesmus indicus R. Br. on streptozotocin-induced diabetic rats.

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Journal:  Int J Diabetes Dev Ctries       Date:  2008-01

10.  Effect of Tinospora cordifolia on experimental diabetic neuropathy.

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Journal:  Indian J Pharmacol       Date:  2012 Sep-Oct       Impact factor: 1.200
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