Literature DB >> 10720452

Use of mathematical model to predict hemodynamics in cavopulmonary anastomosis with persistent forward flow.

G Pennati1, F Migliavacca, G Dubini, R Pietrabissa, R Fumero, M R de Leval.   

Abstract

BACKGROUND: The bidirectional cavopulmonary anastomosis with additional pulmonary blood flow is used as a staged procedure or a definitive palliation of univentricular hearts. In this paper the flow competition occurring between the caval and the pulmonary flows is investigated. The hemodynamics in the superior vena cava and the blood flow distribution into the lungs, as well as the systemic arterial oxygen availability, are correlated with the severity of the right ventricle outflow tract obstruction and the pulmonary arteriolar resistance.
MATERIALS AND METHODS: Computer models of the pre- and postoperative hemodynamics of univentricular hearts were developed. The effects of increasing severity of the right ventricle outflow tract obstruction, with a pulmonary arteriolar resistance ranging from 0.8 to 7.9 nonindexed Woods units, were simulated.
RESULTS: The study indicates that the presence of an additional pulmonary blood flow from the native pulmonary artery may be beneficial. Since an excessive additional blood flow may cause central venous hypertension, its optimal value should be chosen according to the value of pulmonary arteriolar resistance. The model was utilized to simulate four clinical cases.
CONCLUSIONS: The simulations show that the model can predict the postoperative hemodynamics and could therefore be usefully applied to predict quantitatively the effect of the native pulmonary blood flow following bidirectional cavopulmonary anastomosis. Copyright 2000 Academic Press.

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Mesh:

Year:  2000        PMID: 10720452     DOI: 10.1006/jsre.1999.5799

Source DB:  PubMed          Journal:  J Surg Res        ISSN: 0022-4804            Impact factor:   2.192


  6 in total

1.  A viable therapeutic option: mechanical circulatory support of the failing Fontan physiology.

Authors:  Amy L Throckmorton; Sergio Lopez-Isaza; Emily A Downs; Steven G Chopski; James J Gangemi; William Moskowitz
Journal:  Pediatr Cardiol       Date:  2013-02-15       Impact factor: 1.655

2.  Exercise capacity in the Bidirectional Glenn physiology: Coupling cardiac index, ventricular function and oxygen extraction ratio.

Authors:  Carolina Vallecilla; Reza H Khiabani; Phillip Trusty; Néstor Sandoval; Mark Fogel; Juan Carlos Briceño; Ajit P Yoganathan
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Review 3.  Modeling the Fontan circulation: where we are and where we need to go.

Authors:  C G DeGroff
Journal:  Pediatr Cardiol       Date:  2007-10-05       Impact factor: 1.655

4.  Computational fluid dynamics in paediatric cardiac surgery.

Authors:  F Migliavacca; G Dubini; M de Leval
Journal:  Images Paediatr Cardiol       Date:  2000-01

5.  Computational Fluid Dynamics Characterization of Two Patient-Specific Systemic-to-Pulmonary Shunts before and after Operation.

Authors:  Neichuan Zhang; Haiyun Yuan; Xiangyu Chen; Jiawei Liu; Qifei Jian; Meiping Huang; Kai Zhang
Journal:  Comput Math Methods Med       Date:  2019-02-03       Impact factor: 2.238

6.  Computational fluid dynamics investigation of the novel hybrid comprehensive stage II operation.

Authors:  Marwan Hameed; Ray Prather; Eduardo Divo; Alain Kassab; David Nykanen; Michael Farias; William M DeCampli
Journal:  JTCVS Open       Date:  2021-04-27
  6 in total

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