| Literature DB >> 10720294 |
J I Sirven1, M Sperling, D Naritoku, S Schachter, D Labar, M Holmes, A Wilensky, J Cibula, D M Labiner, D Bergen, R Ristanovic, J Harvey, R Dasheiff, G L Morris, C A O'Donovan, L Ojemann, D Scales, M Nadkarni, B Richards, J D Sanchez.
Abstract
The authors assessed the efficacy, safety, and tolerability of vagus nerve stimulation (VNS) for refractory epilepsy in 45 adults 50 years of age and older. They determined seizure frequency, adverse effects, and quality of life. At 3 months, 12 patients had a >50% decrease in seizure frequency; at 1 year, 21 of 31 studied individuals had a >50% seizure decrease. Side effects were mild and transient. Quality of life scores improved significantly with time.Entities:
Mesh：
Year: 2000 PMID： 10720294 DOI： 10.1212/wnl.54.5.1179
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910