| Literature DB >> 10719621 |
L Khalifa1, M J Rosales, C Mascaro, J Karolak-Wojciechowska, N Bsiri, P Brouant, J Barbe.
Abstract
The synthesis of several acridinic thioethers is described. Compounds prepared were tested in vitro as potential drugs against the opportunistic infection known as cryptosporidiosis. With a view to predict activity, the quantitative structure-activity relationships were investigated. Correlations between experimental data and either log P or pKa are discussed.Entities:
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Year: 2000 PMID： 10719621 DOI： 10.1055/s-0031-1300183
Source DB: PubMed Journal: Arzneimittelforschung ISSN： 0004-4172