Literature DB >> 10717246

Expression of hnRNP A2/B1 proteins in human cancer cell lines.

H Satoh1, H Kamma, H Ishikawa, H Horiguchi, M Fujiwara, Y T Yamashita, M Ohtsuka, K Sekizawa.   

Abstract

The overexpression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is recently reported informative as a marker of lung cancer for early detection. To examine whether the expression of the proteins is specific for lung cancer, immunological analyses were performed both in lung and non-lung cancer cell lines. In immunostaining and Western blotting, the expression of A2/B1 was observed not only in the lung cancer cells but also in non-lung cancer cells. The expression of hnRNP A2/B1 is not specific for lung cancer and quantitative determination of A2/B1 is required to elucidate their significance in carcinogenesis.

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Year:  2000        PMID: 10717246     DOI: 10.3892/ijo.16.4.763

Source DB:  PubMed          Journal:  Int J Oncol        ISSN: 1019-6439            Impact factor:   5.650


  6 in total

1.  Expression of heterogeneous nuclear ribonucleoproteins A2 and b1 in the thyroid follicular cells.

Authors:  Yukiko Yano; Wenwen Wu; Hiroshi Kamma; Masachika Fujiwara; Hisato Hara; Tohru Yashiro; Ei Ueno; Masanao Miwa; Yuji Aiyoshi
Journal:  Endocr Pathol       Date:  2005       Impact factor: 3.943

2.  Elevated copper remodels hepatic RNA processing machinery in the mouse model of Wilson's disease.

Authors:  Jason L Burkhead; Martina Ralle; Phillip Wilmarth; Larry David; Svetlana Lutsenko
Journal:  J Mol Biol       Date:  2010-12-10       Impact factor: 5.469

3.  Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets.

Authors:  Manti Guha; Weigang Tang; Neal Sondheimer; Narayan G Avadhani
Journal:  Biochim Biophys Acta       Date:  2010-02-11

4.  HnRNP A2/B1 proteins in nontumorous alveolar cells.

Authors:  H Satoh; H Ishikawa; H Kamma; Y T Yamashita; K Sekizawa
Journal:  Lung       Date:  2003       Impact factor: 2.584

5.  Deregulated expression of hnRNP A/B proteins in human non-small cell lung cancer: parallel assessment of protein and mRNA levels in paired tumour/non-tumour tissues.

Authors:  Georgios Boukakis; Meropi Patrinou-Georgoula; Maria Lekarakou; Christos Valavanis; Apostolia Guialis
Journal:  BMC Cancer       Date:  2010-08-17       Impact factor: 4.430

6.  β-Asarone Inhibits Invasion and EMT in Human Glioma U251 Cells by Suppressing Splicing Factor HnRNP A2/B1.

Authors:  Li Li; Mingxia Wu; Chengqiang Wang; Zanyang Yu; Hongmei Wang; Hongyi Qi; Xiaoyu Xu
Journal:  Molecules       Date:  2018-03-16       Impact factor: 4.411

  6 in total

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