BACKGROUND: To utilize the power of latent growth analysis to evaluate changes in postural sway during development in children who are either at high or low risk for developing alcoholism. METHODS: A total of 629 assessments of postural sway have been performed in children and adolescents (n = 126) who were evaluated annually over a 7-year period. RESULTS: Latent curve models indicated that these children/adolescents show a linear decrease in sway with age. Moreover, significantly different rates of change in the amount of sway between high- and low-risk offspring were seen. With the exception of one of the four stances tested, high-risk boys consistently showed a slower rate of improvement with respect to the amount of sway exhibited compared to low-risk boys. In girls, similar rates of improvement with age were seen in high- and low-risk individuals, though in one stance the high-risk girls showed a deterioration (greater sway with increasing age). CONCLUSIONS: Previous reports of increased postural sway in high-risk offspring most likely reflect a developmental delay (high-risk children have greater sway than is appropriate for their age based on normative values by age).
BACKGROUND: To utilize the power of latent growth analysis to evaluate changes in postural sway during development in children who are either at high or low risk for developing alcoholism. METHODS: A total of 629 assessments of postural sway have been performed in children and adolescents (n = 126) who were evaluated annually over a 7-year period. RESULTS: Latent curve models indicated that these children/adolescents show a linear decrease in sway with age. Moreover, significantly different rates of change in the amount of sway between high- and low-risk offspring were seen. With the exception of one of the four stances tested, high-risk boys consistently showed a slower rate of improvement with respect to the amount of sway exhibited compared to low-risk boys. In girls, similar rates of improvement with age were seen in high- and low-risk individuals, though in one stance the high-risk girls showed a deterioration (greater sway with increasing age). CONCLUSIONS: Previous reports of increased postural sway in high-risk offspring most likely reflect a developmental delay (high-risk children have greater sway than is appropriate for their age based on normative values by age).
Authors: Edith V Sullivan; Ty Brumback; Susan F Tapert; Rosemary Fama; Devin Prouty; Sandra A Brown; Kevin Cummins; Wesley K Thompson; Ian M Colrain; Fiona C Baker; Michael D De Bellis; Stephen R Hooper; Duncan B Clark; Tammy Chung; Bonnie J Nagel; B Nolan Nichols; Torsten Rohlfing; Weiwei Chu; Kilian M Pohl; Adolf Pfefferbaum Journal: Neuropsychology Date: 2016-01-11 Impact factor: 3.295
Authors: Tam T Nguyen-Louie; Georg E Matt; Joanna Jacobus; Irene Li; Claudia Cota; Norma Castro; Susan F Tapert Journal: Alcohol Clin Exp Res Date: 2017-10-30 Impact factor: 3.455
Authors: Reagan R Wetherill; Sunita Bava; Wesley K Thompson; Veronique Boucquey; Carmen Pulido; Tony T Yang; Susan F Tapert Journal: Brain Res Date: 2011-11-11 Impact factor: 3.252