Literature DB >> 10713696

Mammary gland oncogenes as indicators of pathways important in mammary gland development.

C Dickson1, A Creer, V Fantl.   

Abstract

The identification of dominant acting proto-oncogenes in mammary tumors from mice and humans has highlighted a number of signal transduction pathways that have subsequently been shown to have a role in normal mammary growth and differentiation. Here we describe the use of two different transgenic mouse strategies to investigate the function of two of these signalling pathways in the normal growth and differentiation of the mouse mammary gland during pregnancy.

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Year:  2000        PMID： 10713696     DOI： 10.1038/sj.onc.1203267

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  4 in total

1.  ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells.

Authors:  Rebecca S Muraoka; Anne E G Lenferink; Brian Law; Elizabeth Hamilton; Dana M Brantley; L Renee Roebuck; Carlos L Arteaga
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

2.  The Ron receptor tyrosine kinase negatively regulates mammary gland branching morphogenesis.

Authors:  Sara E Meyer; Glendon M Zinser; William D Stuart; Peterson Pathrose; Susan E Waltz
Journal:  Dev Biol       Date:  2009-07-01       Impact factor: 3.582

Review 3.  Mammary cancer susceptibility: human genes and rodent models.

Authors:  Claude Szpirer; Josiane Szpirer
Journal:  Mamm Genome       Date:  2007-12-01       Impact factor: 2.957

4.  Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy.

Authors:  E Y Lin; A V Nguyen; R G Russell; J W Pollard
Journal:  J Exp Med       Date:  2001-03-19       Impact factor: 14.307
  4 in total

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