Literature DB >> 10713649

A reversible bilateral renal artery stenosis in association with antiphospholipid syndrome.

G I Remondino1, E Mysler, M N Pissano, M C Furattini, M C Basta, J L Presas, A Allievi.   

Abstract

We describe a 26-year-old white female with a history of Raynaud phenomenon, erythema nodosum, polyarthralgias, migraine, vertigo, seizures, transient ischemic attacks, one fetal loss, and false positive VDRL, who developed milk hypertension without overt lupus nephritis. She had positive antinuclear antibodies (ANA) and double-stranded deoxyribonucleic acid (dsDNA) antibodies. The lupus anticoagulant test (LAC) and cardiolipins antibodies (aCL) were positive. She was diagnosed as having a Systemic Lupus Erythematosus-like illness (SLE-like) with 'secondary' antiphospholipid syndrome (APS). Renal spiral computed tomography (CT) with intravenous (IV) contrast showed bilateral renal artery stenosis. Anticoagulation with acenocumarol was started. She became normotensive without antihypertensive drugs five months later. A follow-up renal spiral CT showed complete recanalization of both renal arteries, making thrombosis the more likely culprit pathology in the stenosis. After two years follow up the patient is normotensive. She remains on acenocumarol.

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Year:  2000        PMID: 10713649     DOI: 10.1177/096120330000900112

Source DB:  PubMed          Journal:  Lupus        ISSN: 0961-2033            Impact factor:   2.911


  7 in total

1.  Antiphospholipid antibodies attenuate endothelial repair and promote neointima formation in mice.

Authors:  Victoria Ulrich; Eddy S Konaniah; Wan-Ru Lee; Sadiksha Khadka; Yu-Min Shen; Joachim Herz; Jane E Salmon; David Y Hui; Philip W Shaul; Chieko Mineo
Journal:  J Am Heart Assoc       Date:  2014-10-14       Impact factor: 5.501

Review 2.  Renal artery stenosis with significant proteinuria may be reversed after nephrectomy or revascularization in patients with the antiphospholipid antibody syndrome: a case series and review of the literature.

Authors:  Hagit Peleg; Michael Bursztyn; Nurit Hiller; Tiberiu Hershcovici
Journal:  Rheumatol Int       Date:  2010-07-28       Impact factor: 2.631

3.  Renal artery thrombosis in a pediatric case of systemic lupus erythematosus without antiphospholipid antibodies.

Authors:  Koji Tsugawa; Hiroshi Tanaka; Masanobu Kudo; Tohru Nakahata; Etsuro Ito
Journal:  Pediatr Nephrol       Date:  2005-07-21       Impact factor: 3.714

Review 4.  Renal involvement in the antiphospholipid syndrome (APS)-APS nephropathy.

Authors:  Maria G Tektonidou
Journal:  Clin Rev Allergy Immunol       Date:  2009-06       Impact factor: 8.667

Review 5.  Renal involvement in antiphospholipid syndrome.

Authors:  Savino Sciascia; Maria José Cuadrado; Munther Khamashta; Dario Roccatello
Journal:  Nat Rev Nephrol       Date:  2014-03-18       Impact factor: 28.314

Review 6.  New Insights in the Pathophysiology of Antiphospholipid Syndrome.

Authors:  Anastasia Sacharidou; Philip W Shaul; Chieko Mineo
Journal:  Semin Thromb Hemost       Date:  2017-01-27       Impact factor: 6.398

7.  Antiphospholipid (Hughes) syndrome: beyond pregnancy morbidity and thrombosis.

Authors:  Maria Mialdea; Shirish R Sangle; David P D'Cruz
Journal:  J Autoimmune Dis       Date:  2009-05-19
  7 in total

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