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Literature DB >> 10712900

NK cell receptors: of missing sugar and missing self.

Abstract

Natural killer cells in mice detect cells in distress using lectin-like receptors that bind to self-MHC class I molecules. A new co-crystal structure suggests how NK cell maturation and attack may be mediated by receptor interaction at two distinct sites on the MHC class I molecule, both involving glycosylation.

Entities: Chemical Species

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Year: 2000 PMID： 10712900 DOI： 10.1016/s0960-9822(00)00350-x

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

7 in total

1. Synergistic interactions of the two classes of ligand, sialyl-Lewis(a/x) fuco-oligosaccharides and short sulpho-motifs, with the P- and L-selectins: implications for therapeutic inhibitor designs.

Authors: Christine Galustian; Robert A Childs; Mark Stoll; Hideharu Ishida; Makoto Kiso; Ten Feizi
Journal: Immunology Date: 2002-03 Impact factor: 7.397

Review 2. Roles for major histocompatibility complex glycosylation in immune function.

Authors: Sean O Ryan; Brian A Cobb
Journal: Semin Immunopathol Date: 2012-03-30 Impact factor: 9.623

3. Progress in deciphering the information content of the 'glycome'--a crescendo in the closing years of the millennium.

Authors: T Feizi
Journal: Glycoconj J Date: 2000 Jul-Sep Impact factor: 2.916

4. Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster.

Authors: Nathan T Mortimer; Mary L Fischer; Ashley L Waring; Pooja Kr; Balint Z Kacsoh; Susanna E Brantley; Erin S Keebaugh; Joshua Hill; Chris Lark; Julia Martin; Pravleen Bains; Jonathan Lee; Alysia D Vrailas-Mortimer; Todd A Schlenke
Journal: Proc Natl Acad Sci U S A Date: 2021-09-28 Impact factor: 12.779

NK cell receptors: of missing sugar and missing self.

1. Synergistic interactions of the two classes of ligand, sialyl-Lewis(a/x) fuco-oligosaccharides and short sulpho-motifs, with the P- and L-selectins: implications for therapeutic inhibitor designs.

Review 2. Roles for major histocompatibility complex glycosylation in immune function.

3. Progress in deciphering the information content of the 'glycome'--a crescendo in the closing years of the millennium.

4. Extracellular matrix protein N-glycosylation mediates immune self-tolerance in Drosophila melanogaster.

Review 5. Host glycans and antigen presentation.

Review 6. Natural killer cells and immune-checkpoint inhibitor therapy: Current knowledge and new challenges.

7. CAM and NK Cells.